{"id":9652,"date":"2023-11-27T08:28:00","date_gmt":"2023-11-26T23:28:00","guid":{"rendered":"http:\/\/www.itaya.or.jp\/?p=9652"},"modified":"2023-11-27T00:08:42","modified_gmt":"2023-11-26T15:08:42","slug":"long-covid%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8b%e8%ab%96%e6%96%873","status":"publish","type":"post","link":"https:\/\/www.itaya.or.jp\/?p=9652","title":{"rendered":"Long-COVID\u306b\u95a2\u3059\u308b\u8ad6\u65873"},"content":{"rendered":"\n

Long-COIVD\u306b\u95a2\u3059\u308b\u8ad6\u6587\u7b2c3\u5f3e\u3067\u3059\u3002
\u304d\u3063\u304b\u3051\u306f\u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb\u96fb\u5b50\u72482023\/11\/07\u306b\u8f09\u3063\u3066\u3044\u305f\u8a18\u4e8b\u304b\u3089\u3002
\uff1eCOVID-19\u5f8c\u907a\u75c7\u306e\u539f\u56e0\u306e1\u3064\u306f\u30bb\u30ed\u30c8\u30cb\u30f3\u6e1b\u5c11\u304b<\/a>

\u3053\u306e\u8a18\u4e8b\u306f\u6b21\u306e\u8ad6\u6587\u3092\u3082\u3068\u306b\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\uff1a
\u201dSerotonin reduction in post-acute sequelae of viral infection<\/a>
\uff08\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306e\u6025\u6027\u5f8c\u907a\u75c7\u306b\u304a\u3051\u308b\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u6e1b\u5c11\uff09\u201d
\u51fa\u5178\u306f\u3001Cell\u3000 VOLUME 186, ISSUE 22, P4851-4867.E20, OCTOBER 26, 2023
Opne access\u3067\u3059\u3002


\u4e0a\u8a18\u8ad6\u6587\u306eSummary\u3092\u3044\u3064\u3082\u306e\u3088\u3046\u306bDeepL\u7c21\u6613\u7248\u3067\u8a33\u3057\u3066\u307f\u307e\u3059\u3002
\u300c\u8981\u7d04
COVID-19\uff08PASC\u3001”Long-COIVD”\uff09\u306e\u6025\u6027\u5f8c\u907a\u75c7\u306f\u3001\u4e16\u754c\u7684\u306b\u91cd\u5927\u306a\u4fdd\u5065\u4e0a\u306e\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u75c5\u614b\u751f\u7406\u5b66\u306f\u4e0d\u660e\u3067\u3042\u308a\u3001\u73fe\u5728\u307e\u3067\u306b\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u306f\u898b\u3064\u304b\u3063\u3066\u3044\u306a\u3044\u3002PASC\u306e\u75c5\u56e0\u3092\u8aac\u660e\u3059\u308b\u305f\u3081\u306b\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u6301\u7d9a\u6027\u3001\u6162\u6027\u708e\u75c7\u3001\u51dd\u56fa\u4ea2\u9032\u3001\u81ea\u5f8b\u795e\u7d4c\u6a5f\u80fd\u969c\u5bb3\u306a\u3069\u3044\u304f\u3064\u304b\u306e\u4eee\u8aac\u304c\u7acb\u3066\u3089\u308c\u3066\u3044\u308b\u3002\u3053\u3053\u3067\u306f\u30014\u3064\u306e\u4eee\u8aac\u3059\u3079\u3066\u30921\u3064\u306e\u7d4c\u8def\u3067\u7d50\u3073\u3064\u3051\u3001\u6cbb\u7642\u7684\u4ecb\u5165\u306e\u305f\u3081\u306e\u5b9f\u7528\u7684\u306a\u6d1e\u5bdf\u3092\u63d0\u4f9b\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u63d0\u6848\u3059\u308b\u3002\u6211\u3005\u306f\u3001PASC\u304c\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u6e1b\u5c11\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u305f\u3002\u3059\u306a\u308f\u3061\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u524d\u99c6\u4f53\u3067\u3042\u308b\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u306e\u8178\u7ba1\u5438\u53ce\u306e\u4f4e\u4e0b\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u8caf\u8535\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u8840\u5c0f\u677f\u306e\u6d3b\u6027\u5316\u4ea2\u9032\u3068\u8840\u5c0f\u677f\u6e1b\u5c11\u3001MAO\u3092\u4ecb\u3057\u305f\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u4ee3\u8b1d\u4ea2\u9032\u3067\u3042\u308b\u3002\u672b\u68a2\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u304c\u6e1b\u5c11\u3059\u308b\u3068\u3001\u8ff7\u8d70\u795e\u7d4c\u306e\u6d3b\u52d5\u304c\u963b\u5bb3\u3055\u308c\u3001\u6d77\u99ac\u306e\u53cd\u5fdc\u3068\u8a18\u61b6\u304c\u640d\u306a\u308f\u308c\u308b\u3002\u3053\u308c\u3089\u306e\u77e5\u898b\u306f\u3001Long-COVID\u306b\u304a\u3051\u308b\u30a6\u30a4\u30eb\u30b9\u6301\u7d9a\u306b\u4f34\u3046\u795e\u7d4c\u8a8d\u77e5\u75c7\u72b6\u306e\u8aac\u660e\u3068\u306a\u308a\u3001\u4ed6\u306e\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u5f8c\u75c7\u5019\u7fa4\u306b\u3082\u53ca\u3076\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u300d

\u30b0\u30e9\u30d5\u30a3\u30ab\u30eb\u30fb\u30a2\u30d6\u30b9\u30c8\u30e9\u30af\u30c8
\"\"

COVID-19\u306e\u6025\u6027\u5f8c\u907a\u75c7\u306f\u3001Long-COIVD\u3068\u304b\u3001
Post-acute sequelae SARS-CoV-2 infection (PASC)\u3068\u547c\u3073\u307e\u3059\u304c\u3001
\u3053\u308c\u3089\u306f\u3001\u4e16\u754c\u7684\u306b\u91cd\u5927\u306a\u5065\u5eb7\u4e0a\u306e\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u304c\u3001
\u75c5\u614b\u751f\u7406\u5b66\u306f\u4e0d\u660e\u3067\u3042\u308a\u3001\u73fe\u5728\u307e\u3067\u306b\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u306f\u898b\u3064\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002

Long-COIVD\u306e\u5f8c\u907a\u75c7\u3092\u3001
\u5f53\u521d\u3001Post-Acute-Covid-Syndrome (PACS)\u3068\u547c\u3093\u3067\u3044\u307e\u3057\u305f\u3002
\u305d\u306e\u3042\u305f\u308a\u306e\u3053\u3068\u306f\u3001\u5f53\u9662\u30d6\u30ed\u30b0\u3067\u3082\u53d6\u308a\u4e0a\u3052\u307e\u3057\u305f\u3002
\uff1ePost-acute COVID-19 syndrome1<\/a>\uff5e4

PASC\u3068PACS\u306f\u540c\u3058\u306a\u306e\u304b\u3069\u3046\u304b\u308f\u304b\u308a\u307e\u305b\u3093\u3002
\u305f\u3060\u3001\u8ad6\u6587\u3092\u8aad\u3093\u3067\u3044\u304f\u3068\u3001\u4f55\u3068\u306a\u304f\u3001
PACS\u306f\u5f37\u3044\u80ba\u708e\u306a\u3069\u306e\u5f8c\u306e\u547c\u5438\u5668\u969c\u5bb3\u3084\u3001
\u8133\u8840\u7ba1\u969c\u5bb3\u3001\u5fc3\u8840\u7ba1\u969c\u5bb3\u306a\u3069\u306e\u5f8c\u907a\u75c7\u3082\u5e83\u304f\u542b\u3080\u306e\u306b\u5bfe\u3057\u3001
\u3053\u306e\u8ad6\u6587\u3067\u53d6\u308a\u4e0a\u3052\u3066\u3044\u308bPASC\u306f\u3001
\u5f8c\u907a\u75c7\u306e\u4e2d\u3067\u3082\u3001\u5026\u6020\u611f\u3084BrianFog\uff08\u8133\u9727\uff09\u306a\u3069\u3001
\u7279\u306b\u81ea\u5f8b\u795e\u7d4c\u75c7\u72b6\u3084\u7cbe\u795e\u8a8d\u77e5\u75c7\u72b6\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u5f8c\u907a\u75c7\u3092
\u6307\u3059\u69d8\u306a\u6c17\u304c\u3057\u307e\u3059\u3002

PASC\u306e\u75c5\u56e0\u3092\u8aac\u660e\u3059\u308b\u305f\u3081\u306b\u3001\u4e00\u822c\u7684\u306b
\u30a6\u30a4\u30eb\u30b9\u306e\u6301\u7d9a\u6027\u3001\u6162\u6027\u708e\u75c7\u3001\u51dd\u56fa\u4ea2\u9032\u3001\u81ea\u5f8b\u795e\u7d4c\u6a5f\u80fd\u969c\u5bb3\u306a\u3069
\u3044\u304f\u3064\u304b\u306e\u4eee\u8aac\u304c\u7acb\u3066\u3089\u308c\u3066\u3044\u307e\u3059\u3002
\u3053\u306e\u8ad6\u6587\u3067\u306f\u3001\u3053\u306e4\u3064\u306e\u4eee\u8aac\u3059\u3079\u3066\u30921\u3064\u306e\u7d4c\u8def\u3067\u7d50\u3073\u3064\u3051\u3001
\u6cbb\u7642\u7684\u4ecb\u5165\u306b\u5b9f\u7528\u7684\u306a\u6d1e\u5bdf\u3092\u4e0e\u3048\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u63d0\u6848\u3055\u308c\u3066\u3044\u307e\u3059\u3002

\u307e\u305a\u3001\u6025\u6027\u611f\u67d3\u304b\u30893\uff5e22\u30f5\u6708\u5f8c\u306b\u75c7\u72b6\u304c\u6301\u7d9a\u3057\u305f
58\u4eba\u306eLong-COIVD\u60a3\u8005\u3092\u5bfe\u8c61\u306b
\u6025\u6027COVID-19\u60a3\u800560\u4eba\u304a\u3088\u3073
COVID-19\u304b\u3089\u7121\u75c7\u72b6\u3067\u56de\u5fa9\u3057\u305f\u60a3\u800530\u4eba\u3068\u3092
\u6a19\u7684\u8840\u6f3f\u30e1\u30bf\u30dc\u30ed\u30df\u30af\u30b9\uff08\u4ee3\u8b1d\u7269\u3092\u7db2\u7f85\u7684\u306b\u89e3\u6790\u3059\u308b\u65b9\u6cd5\uff09\u3092
\u5b9f\u65bd\u3057\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002

COVID-19\u306e\u6025\u6027\u671f\u3068\u6025\u6027\u671f\u5f8c\u306e\u4e21\u65b9\u3067
\u30ec\u30d9\u30eb\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u5206\u5b50\u7fa4\u304c\u540c\u5b9a\u3055\u308c\u3001
\u305d\u306e\u3046\u3061\u6700\u3082\u91cd\u8981\u306a\u3082\u306e\u306f
\u30bb\u30ed\u30c8\u30cb\u30f3\uff085-\u30d2\u30c9\u30ed\u30ad\u30b7\u30c8\u30ea\u30d7\u30bf\u30df\u30f3\u30015-HT\uff09\u3067\u3057\u305f\u3002
\"\"
\u30b0\u30e9\u30d5\u306e\u898b\u65b9\u304c\u3088\u304f\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u306e\u3067\u3059\u304c\u3001
\u3044\u308d\u3044\u308d\u306a\u4ee3\u8b1d\u7523\u7269\u306e\u91cf\u3092\u3001
COVID-19\u306e\u60a3\u8005\u3055\u3093\u3068\u5065\u5eb7\u306a\u4eba\u3067\u6bd4\u3092\u6c42\u3081\u3066\u9806\u756a\u306b\u4e26\u3079\u305f\u3082\u306e\u3068\u601d\u3044\u307e\u3059\u3002
\u4e00\u756a\u5de6Serotonin\u304c\u3042\u308a\u3001COVID-19\u3067\u6700\u3082\u5c11\u306a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002

\u6b21\u306b\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u6e1b\u5c11\u304cCOVID-19\u306b\u7279\u6709\u306a\u306e\u304b\u3001
\u4ed6\u306e\u6025\u6027\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u3067\u3082\u540c\u69d8\u306e\u6e1b\u5c11\u304c\u898b\u3089\u308c\u308b\u306e\u304b\u3092\u8abf\u3079\u305f\u305d\u3046\u3067\u3059\u3002
\u975eSARS-CoV-2\u5168\u8eab\u6027\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u60a3\u800533\u4eba\u306e
\u8840\u6f3f\u4e2d\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3057\u3001
\u5065\u5e38\u5bfe\u7167\u800520\u4eba\u3068\u6bd4\u8f03\u3057\u305f\u3068\u3053\u308d\u3001
\u6025\u6027COVID-19\u306e\u5834\u5408\u3068\u540c\u69d8\u306b\u3001
\u30bb\u30ed\u30c8\u30cb\u30f3\u30ec\u30d9\u30eb\u306f\u4ed6\u306e\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306b\u3088\u3063\u3066\u5f37\u304f\u4f4e\u4e0b\u3057\u3066\u3044\u305f\u305d\u3046\u3067\u3059\u3002
\u3053\u308c\u306f\u5168\u8eab\u6027\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306e
\u3088\u308a\u4e00\u822c\u7684\u306a\u7279\u5fb4\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002

\u3053\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u6e1b\u5c11\u304c\u306a\u305c\u8d77\u3053\u308b\u306e\u304b\u3092\u3001
\u3055\u3089\u306b\u8e0f\u307f\u8fbc\u3093\u3067\u8abf\u3079\u3066\u307f\u305f\u305d\u3046\u3067\u3059\u3002
\u52d5\u7269\u5b9f\u9a13\u3067\u3001\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u7b49\u3092\u8d77\u3053\u3055\u305b\u308b\u3068\u3001
\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u523a\u6fc0\u907a\u4f1d\u5b50(ISG)\u306e\u30ec\u30d9\u30eb\u304c\u5f37\u304f\u4e0a\u6607\u3059\u308b\u306e\u3060\u305d\u3046\u3067\u3059\u3002
\u305d\u3057\u3066\u3001\u5b9f\u969b\u306bI\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u306e\u6301\u7d9a\u7684\u306a\u4e0a\u6607\u304c
Long COVID\u60a3\u8005\u3067\u89b3\u5bdf\u3055\u308c\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u3002
\u3053\u308c\u306f\u3001TLR3\u306b\u3088\u308b\u30a6\u30a4\u30eb\u30b9RNA\u611f\u77e5\u3068
I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u8a98\u5c0e\u304c\u4ea2\u9032\u3057\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u67af\u6e07\u306b\u3064\u306a\u304c\u308b\u69d8\u3067\u3059\u3002

\u3053\u306e\u8ad6\u6587\u3067\u306f\u3055\u3089\u306b\u3001
\u30a6\u30a4\u30eb\u30b9\u306b\u3088\u308b\u708e\u75c7\u304c\u30bb\u30ed\u30c8\u30cb\u30f3\u30ec\u30d9\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u30e1\u30ab\u30cb\u30ba\u30e0
\u306b\u3064\u3044\u3066\u3082\u691c\u8a0e\u3057\u3066\u3044\u307e\u3059\u3002

\u5faa\u74b0\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u5927\u90e8\u5206\u306f\u6d88\u5316\u7ba1\u3067\u7523\u751f\u3055\u308c\u3001
\u305d\u3053\u3067\u98df\u990c\u6027\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u304b\u3089\u30a8\u30f3\u30c6\u30ed\u30af\u30ed\u30de\u30d5\u30a3\u30f3\u7d30\u80de\u3067\u5408\u6210\u3055\u308c\u307e\u3059\u3002
\u6025\u6027COVID-19\u60a3\u8005\u3084\u3001\u3055\u3089\u306bLong-COIVD\u60a3\u8005\u3067\u306f
\u8840\u6f3f\u4e2d\u306e\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u6fc3\u5ea6\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u305d\u3046\u3067\u3059\u3002

\u9014\u4e2d\u3061\u3087\u3063\u3068\u7701\u7565\u3057\u307e\u3059\u304c\u3001
\u30a6\u30a4\u30eb\u30b9\u6027RNA\u306b\u3088\u3063\u3066\u8a98\u767a\u3055\u308c\u305f\u708e\u75c7\u306b\u3088\u3063\u3066\u3001
\u8178\u306e\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u53d6\u308a\u8fbc\u307f\u304c\u969c\u5bb3\u3055\u308c\u3001
\u5168\u8eab\u6027\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u67af\u6e07\u304c\u5f15\u304d\u8d77\u3055\u308c\u308b\u306e\u3060\u305d\u3046\u3067\u3059\u3002

\u3055\u3089\u306b\u3001\u30a6\u30a4\u30eb\u30b9\u6027\u708e\u75c7\u3067\u306f\u3001\u51dd\u56fa\u6a5f\u80fd\u304c\u4ea2\u9032\u3057\u3001
\u8840\u5c0f\u677f\u51dd\u96c6\u304c\u9855\u8457\u306b\u5897\u5f37\u3055\u308c\u308b\u3089\u3057\u304f\u3001
\u30a6\u30a4\u30eb\u30b9\u306e\u708e\u75c7\u304c\u8840\u5c0f\u677f\u306e\u6d3b\u6027\u5316\u3092\u4fc3\u9032\u3057\u3001
\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u4f9d\u5b58\u7684\u306b\u51dd\u56fa\u80fd\u4ea2\u9032\u3068\u8840\u5c0f\u677f\u6e1b\u5c11\u3092\u5f15\u304d\u8d77\u3053\u3059\u3068\u306e\u3053\u3068\u3002

\u5faa\u74b0\u30bb\u30ed\u30c8\u30cb\u30f3\u306f\u8178\u7ba1\u5185\u306e\u30a8\u30f3\u30c6\u30ed\u30af\u30ed\u30de\u30d5\u30a3\u30f3\u7d30\u80de\u3067\u5408\u6210\u3055\u308c\u305f\u306e\u3061\u3001
\u8840\u5c0f\u677f\u5185\u306b\u8f38\u9001\u3055\u308c\u3066\u3001\u8caf\u8535\u3055\u308c\u308b\u306e\u3060\u305d\u3046\u3067\u3059\u304c\u3001\u30a6\u30a4\u30eb\u30b9\u6027\u708e\u75c7\u3067\u306f\u3001
\u8840\u5c0f\u677f\u3092\u4ecb\u3057\u305f\u5168\u8eab\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u8f38\u9001\u3082\u969c\u5bb3\u3055\u308c\u3066\u3044\u308b\u308f\u3051\u3067\u3059\u3002

\u3055\u3089\u306b\u3001\u30e2\u30ce\u30a2\u30df\u30f3\u30aa\u30ad\u30c0\u30fc\u30bc\uff08MAO\uff09\u306b\u3088\u308b
\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u5206\u89e3\u3082\u4ea2\u9032\u3057\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u3002

Long-COIVD\u3067\u306f\u3001\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u3082\u91cd\u8981\u306a\u75c7\u72b6\u306e\u4e00\u3064\u3067\u3059\u3002
\u77ed\u671f\u8a18\u61b6\u306e\u7372\u5f97\u306f\u6d77\u99ac\u306b\u3088\u3063\u3066\u99c6\u52d5\u3055\u308c\u3066\u3044\u3066\u3001
COVID-19\u60a3\u8005\u3067\u306f\u6d77\u99ac\u306e\u6d3b\u52d5\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u3002

\u30bb\u30ed\u30c8\u30cb\u30f3\u306f\u6d77\u99ac\u306e\u6a5f\u80fd\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u304c\u3001
\u8133\u5185\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u30ec\u30d9\u30eb\u306f\u30a6\u30a4\u30eb\u30b9\u6027\u708e\u75c7\u306e\u5f71\u97ff\u3092\u53d7\u3051\u306a\u304b\u3063\u305f\u3053\u3068\u304b\u3089
\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u672b\u68a2\u3067\u306e\u6e1b\u5c11\u304c\u8a8d\u77e5\u969c\u5bb3\u306e\u539f\u56e0\u3067\u3042\u308b\u3068\u306e\u3053\u3068\u3067\u3057\u305f\u3002

\u306a\u3093\u304b\u3001\u3066\u3093\u3053\u76db\u308a\u306e\u8ad6\u6587\u3067\u3001
\u304b\u306a\u308a\u6d88\u5316\u4e0d\u826f\u3067\u7533\u3057\u8a33\u3042\u308a\u307e\u305b\u3093\u3002

\u3068\u308a\u3042\u3048\u305a\u3001
SARS-COV2\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u30a6\u30a4\u30eb\u30b9\u75be\u60a3\u306b\u611f\u67d3\u3057\u305f\u5834\u5408\u3001
\u8178\u7ba1\u3067\u306e\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u5438\u53ce\u304c\u969c\u5bb3\u3055\u308c\u3001
\u305d\u306e\u7d50\u679c\u3001\u8178\u5185\u306e\u30a8\u30f3\u30c6\u30ed\u30af\u30ed\u30de\u30d5\u30a3\u30f3\u7d30\u80de\u3067\u306e
\u30bb\u30ed\u30c8\u30cb\u30f3\u5408\u6210\u304c\u4f4e\u4e0b\u3057\u3001
\u3055\u3089\u306b\u3001\u8840\u6db2\u4e2d\u3067\u51dd\u56fa\u6a5f\u80fd\u304c\u4ea2\u9032\u3059\u308b\u305f\u3081\u3001
\u8840\u6813\u5f62\u6210\u304c\u4ea2\u9032\u3001\u7d50\u679c\u7684\u306b\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u8caf\u8535\u5eab\u3067\u3042\u308b\u8840\u5c0f\u677f\u3082\u6e1b\u5c11\u3001
\u3055\u3089\u306b\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u5206\u89e3\u304c\u4ea2\u9032\u3055\u308c\u308b\u305f\u3081\u3001
\u307e\u3059\u307e\u3059\u30bb\u30ed\u30c8\u30cb\u30f3\u304c\u67af\u6e07\u3059\u308b\u3002
\u305d\u306e\u7d50\u679c\u3001\u6d77\u99ac\u306e\u6d3b\u52d5\u304c\u4f4e\u4e0b\u3059\u308b\u3002

\u3053\u308c\u304cLong-COIVD\uff0cPASC\u306e\u672c\u4f53\u3060\u308d\u3046\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002

\u8840\u6813\u5f62\u6210\u304c\u4ea2\u9032\u3059\u308b\u3068\u3044\u3046\u8a71\u306f\u3001
COVID-19\u304c\u6d41\u884c\u3057\u3066\u304d\u305f\u3053\u308d\u304b\u3089\u805e\u3044\u3066\u3044\u307e\u3059\u3002
SARS-COV2\u30a6\u30a4\u30eb\u30b9\u306e\u30b9\u30d1\u30a4\u30af\u86cb\u767d\u304c\u3001
ACE2\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u3001\u305d\u308c\u3092\u8db3\u304c\u304b\u308a\u306b\u7d30\u80de\u306b\u4fb5\u5165\u3059\u308b
\u3068\u3044\u3046\u306e\u304c\u3001\u521d\u671f\u306eSARS-COV2\u306e\u632f\u308b\u821e\u3044\u3067\u3057\u305f\u3002
\uff08\u5909\u7570\u578b\u306fACE2\u3092\u4ecb\u3055\u306a\u3044\u7d4c\u8def\u3067\u4fb5\u5165\u3059\u308b\u3068\u3082\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\uff09

\u305d\u306e\u969b\u3001\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u3067\u3053\u308c\u304c\u8d77\u3053\u308b\u3068
\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u304c\u969c\u5bb3\u3092\u53d7\u3051\u3001\u8840\u6813\u3092\u8d77\u3053\u3057\u3084\u3059\u304f\u306a\u308b\u69d8\u3067\u3059\u3002
\u2191
\u3053\u308c\u3001\uff4dRNA\u30ef\u30af\u30c1\u30f3\u306e\u7406\u8ad6\u304c\u3001
\u8eab\u4f53\u306b\u30b9\u30d1\u30a4\u30af\u86cb\u767d\u3092\u4f5c\u3089\u305b\u3066
\u514d\u75ab\u7d30\u80de\u306b\u899a\u3048\u3055\u305b\u3088\u3046\u3068\u3044\u3046\u3082\u306e\u3067\u3059\u304b\u3089\u3001
\u30ef\u30af\u30c1\u30f3\u306b\u3082\u8840\u6813\u75c7\u3092\u8d77\u3053\u3057\u3084\u3059\u3044\u50be\u5411\u306f\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u3002
\u3068\u3059\u308b\u3068\u3001\u6642\u306b\u30ef\u30af\u30c1\u30f3\u3067\u3082
PASC\u306b\u4f3c\u305f\u75c7\u72b6\u304c\u3067\u308b\u53ef\u80fd\u6027\u3082\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002

Long-COIVD\u306e\u65b9\u3082\u3001\u30ef\u30af\u30c1\u30f3\u5f8c\u306e\u4e0d\u8abf\u306e\u4eba\u3082\u3001
\u7d50\u5c40\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u6e1b\u5c11\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002
\u6cbb\u7642\u306f\u3053\u3053\u306b\u7126\u70b9\u3092\u5408\u308f\u305b\u308b\u306e\u304c\u3044\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002




<\/p>\n","protected":false},"excerpt":{"rendered":"

Long-COIVD\u306b\u95a2\u3059\u308b\u8ad6\u6587\u7b2c3\u5f3e\u3067\u3059\u3002\u304d\u3063\u304b\u3051\u306f\u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb\u96fb\u5b50\u72482023\/11\/07\u306b\u8f09\u3063\u3066\u3044\u305f\u8a18\u4e8b\u304b\u3089\u3002\uff1eCOVID-19\u5f8c\u907a\u75c7\u306e\u539f\u56e0\u306e1\u3064\u306f\u30bb\u30ed\u30c8\u30cb\u30f3\u6e1b\u5c11\u304b \u3053\u306e\u8a18\u4e8b\u306f\u6b21\u306e\u8ad6\u6587\u3092\u3082\u3068\u306b\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\uff1a\u201dSe …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[89,6],"tags":[67],"class_list":["post-9652","post","type-post","status-publish","format-standard","hentry","category-covid-19","category-blog","tag-covid-19"],"_links":{"self":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9652","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9652"}],"version-history":[{"count":4,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9652\/revisions"}],"predecessor-version":[{"id":9658,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9652\/revisions\/9658"}],"wp:attachment":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9652"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9652"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9652"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}