{"id":9648,"date":"2023-11-25T08:28:00","date_gmt":"2023-11-24T23:28:00","guid":{"rendered":"http:\/\/www.itaya.or.jp\/?p=9648"},"modified":"2023-11-23T22:54:03","modified_gmt":"2023-11-23T13:54:03","slug":"long-covid%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8b%e8%ab%96%e6%96%872","status":"publish","type":"post","link":"https:\/\/www.itaya.or.jp\/?p=9648","title":{"rendered":"Long-COVID\u306b\u95a2\u3059\u308b\u8ad6\u65872"},"content":{"rendered":"\n

\u524d\u56de\u306f\u3001Long-COIVD\u3068\u8178\u5185\u306e\u771f\u83cc\u304c\u95a2\u9023\u304c\u3042\u308b\u306e\u3067\u306f\uff1f\u3068\u3044\u3046\u8a71\u3067\u3057\u305f\u304c\u3001
\u4eca\u56de\u306f\u3001Long-COIVD\u3068\u30d3\u30bf\u30df\u30f3D\u3068\u306e\u95a2\u9023\u3067\u3059\u3002

\u201dLow Vitamin D Levels Are Associated With Long COVID Syndrome in COVID-19 Survivors
\uff08COVID-19\u751f\u5b58\u8005\u306b\u304a\u3051\u308b\u4f4e\u30d3\u30bf\u30df\u30f3D\u30ec\u30d9\u30eb\u306f\u9577\u3044COVID\u75c7\u5019\u7fa4\u3068\u95a2\u9023\u3059\u308b\uff09\u201d<\/a>
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 10, October 2023, Pages e1106-e1116\uff1a


\u5bfe\u8c61\u306f\u3001COVID-19\u3068\u78ba\u5b9a\u8a3a\u65ad\u3055\u308c\u305f\u6210\u4eba\u60a3\u8005\uff08\u5e74\u9f6218\u6b73\u4ee5\u4e0a\uff09\u306e\u3046\u3061\u3001
2020\u5e743\u6708\u304b\u30895\u6708\u307e\u3067\u306e\u7b2c1\u6b21\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u306e\u6d41\u884c\u671f\u306b
IRCCS Ospedale San Raffaele\u306b\u5165\u9662\u3057\u3001\u305d\u306e\u5f8c\u9000\u9662\u3057\u3001
\u9000\u9662\u5f8c6\u30f5\u6708\u5f8c\u306b\u540c\u65bd\u8a2d\u306eCOVID-19\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u5916\u6765\u3067\u518d\u8a55\u4fa1\u3092\u53d7\u3051\u305f\u60a3\u8005\uff1a
(1)\u30d3\u30bf\u30df\u30f3D\u4ee3\u8b1d\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u4f75\u5b58\u75be\u60a3\uff08\u6162\u6027\u814e\u81d3\u75c5\u3001\u9aa8\u7c97\u9b06\u75c7\uff09\u304a\u3088\u3073\u6cbb\u7642\u85ac\uff08\u6162\u6027\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u3001\u6297\u3066\u3093\u304b\u3093\u85ac\u6cbb\u7642\u3001\u30d3\u30bf\u30df\u30f3D\/\u30ab\u30eb\u30b7\u30a6\u30e0\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3001\u30eb\u30fc\u30d7\/\u30b5\u30a4\u30a2\u30b6\u30a4\u30c9\u7cfb\u5229\u5c3f\u85ac\u306a\u3069\uff09\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u4eba\u306f\u9664\u5916
\uff082\uff09\u5728\u5b85\u7ba1\u7406\u306e\u307f\u3067\u3042\u3063\u305f\u60a3\u8005\u3001\u304a\u3088\u3073\u5165\u9662\u4e2d\u306bICU\u306b\u5165\u9662\u3057\u305f\u60a3\u8005\u306f\u9664\u5916
\uff08\u8efd\u75c7\u3059\u304e\u306e\u4eba\u3001\u91cd\u75c7\u3059\u304e\u306e\u4eba\u306f\u9664\u5916\u3057\u305f\u3068\u3044\u3046\u3053\u3068\u3060\u3068\u601d\u3044\u307e\u3059\uff09
\uff083\uff09\u5165\u9662\u6642\u304a\u3088\u30736\u30f5\u6708\u8ffd\u8de1\u6642\u306b\u8a18\u9332\u3055\u308c\u305f\u533b\u7642\u30c7\u30fc\u30bf\u304c\u5165\u624b\u53ef\u80fd\u306a\u60a3\u8005
\uff084\uff09\u5165\u9662\u6642\u304a\u3088\u30736\u30f5\u6708\u8ffd\u8de1\u6642\u306b\u63a1\u53d6\u3055\u308c\u305f25\uff08OH\uff09\u30d3\u30bf\u30df\u30f3D\u6e2c\u5b9a\u306e\u305f\u3081\u306e\u8840\u6db2\u30b5\u30f3\u30d7\u30eb\u304c\u5165\u624b\u53ef\u80fd\u306a\u60a3\u8005

Long-COIVD\u306e\u8a3a\u65ad\u306f\u30016\u30f5\u6708\u306e\u7d4c\u904e\u89b3\u5bdf\u6642\u306b
\u4f53\u8cea\uff1a\u7121\u529b\u75c7\u3001\u767a\u71b1\u3001\u7b4b\u8089\u75db\u3001\u95a2\u7bc0\u75db
\u5fc3\u80ba\uff1a\u54b3\u55fd\u3001\u547c\u5438\u56f0\u96e3\u3001\u80f8\u75db
\u6d88\u5316\u5668\uff1a\u8179\u75db\u3001\u5410\u304d\u6c17\/\u5614\u5410\u3001 \u4e0b\u75e2\u3001
\u795e\u7d4c\u8a8d\u77e5\uff1a\u982d\u75db\u3001\u8133\u9727\/\u932f\u4e71\u3001
\u8033\u9f3b\u54bd\u5589\uff1a\u54bd\u982d\u75db\u3001\u9f3b\u6f0f\u3001\u8033\u75db
\u611f\u899a\u9818\u57df\uff1a\u55c5\u899a\u4f4e\u4e0b\u3001\u5473\u899a\u7570\u5e38
\u3053\u3046\u3057\u305f\u75c7\u72b6\u30fb\u5fb4\u5019\u3092\u5c11\u306a\u304f\u3068\u30822\u3064\u4ee5\u4e0a\u6709\u3057\u3066\u3044\u3066\u3001
\u4ed6\u306e\u533b\u5b66\u7684\u8a3a\u65ad\u3067\u306f\u8aac\u660e\u3067\u304d\u305a\u3001
\u4ee5\u524d\u306eCOVID-19\u306b\u8d77\u56e0\u3059\u308b\u3068\u3057\u304b\u8003\u3048\u3089\u308c\u306a\u3044\u5834\u5408\u3068\u3057\u305f\u305d\u3046\u3067\u3059\u3002

\u7d50\u679c\uff1a
\u8ffd\u8de1\u8abf\u67fb\u6642\u306b\u8a55\u4fa1\u3057\u305f25(OH)\u30d3\u30bf\u30df\u30f3D\u6fc3\u5ea6\u306f\u3001
Long-COIVD\u306e\u4eba\u306f\u3001\u305d\u3046\u3067\u306a\u3044\u88ab\u9a13\u8005\u3088\u308a\u4f4e\u3044\u3053\u3068\u304c\u89b3\u5bdf\u3055\u308c\u307e\u3057\u305f\u3002
\uff0820.1 vs 23.2ng\/mL\u3001P = 0.03\uff09

\u7279\u306b\u3001\u795e\u7d4c\u8a8d\u77e5\u75c7\u72b6\u3092\u5448\u3057\u305f\u60a3\u8005\u3055\u3093\u3067\u9855\u8457\u3060\u3063\u305f\u305d\u3046\u3067\u3059\u3002
\uff0814.6 vs 20.6 ng\/mL\u3001P = 0.042\uff09

\u305d\u3057\u3066\u3053\u306e\u8ffd\u8de1\u8abf\u67fb\u6642\u306e25(OH)\u30d3\u30bf\u30df\u30f3D\u5024\u306e\u4f4e\u5024\u306f\u3001
\u3053\u306e\u7814\u7a76\u306b\u304a\u3051\u308bLong-COVID\u3068\u6709\u610f\u306b\u95a2\u9023\u3059\u308b
\u552f\u4e00\u306e\u5909\u6570\u3067\u3042\u3063\u305f\u3068\u306e\u3053\u3068\u3002

\u30d3\u30bf\u30df\u30f3D\u3068\u3044\u3046\u3068\u3001\u9aa8\u306e\u4ee3\u8b1d\u304c\u3059\u3050\u306b\u601d\u3044\u6d6e\u304b\u3073\u307e\u3059\u304c\u3001
\u81ea\u7136\u514d\u75ab\u3068\u9069\u5fdc\u514d\u75ab\u306e\u4e21\u65b9\u306b\u95a2\u3059\u308b\u514d\u75ab\u53cd\u5fdc\u3068\u514d\u75ab\u80fd\u3092\u8abf\u7bc0\u3057\u3001
\u6297\u83cc\u304a\u3088\u3073\u6297\u30a6\u30a3\u30eb\u30b9\u514d\u75ab\u53cd\u5fdc\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u3053\u3068\u304c
\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u3002
\uff08\u3053\u306e\u3042\u305f\u308a\u3082\u3046\u5c11\u3057\u52c9\u5f37\u3057\u305f\u3044\u3068\u601d\u3044\u307e\u3059\uff09

\u3053\u306e\u8ad6\u6587\u306e\u8003\u5bdf\u3067\u306f\u3001
\u3055\u3089\u306b\u3001\u5165\u9662\u6642\u306b\u30d3\u30bf\u30df\u30f3D\u6fc3\u5ea6\u304c\u4f4e\u304b\u3063\u305f\u60a3\u8005\u306e3\u5206\u306e2\u306f\u3001
6\u30f5\u6708\u5f8c\u306e\u8ffd\u8de1\u8abf\u67fb\u3067\u3082\u30d3\u30bf\u30df\u30f3D\u4f4e\u5024\u3092\u793a\u3057\u3066\u3044\u305f\u305d\u3046\u3067\u3059\u3002
\u305f\u3060\u300125(OH)\u30d3\u30bf\u30df\u30f3D\u5024\u306e\u5dee\u306b\u75be\u60a3\u306e\u91cd\u75c7\u5ea6\u304c\u5f71\u97ff\u3057\u3066\u3044\u308b\u3053\u3068\u3092
\u652f\u6301\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u304b\u3063\u305f\u3068\u3082\u66f8\u3044\u3066\u3042\u308a\u307e\u3057\u305f\u3002

6\u30f6\u6708\u5f8c\u306bLong-COIVD\u306e\u75c7\u72b6\u3092\u5448\u3057\u3066\u3044\u305f\u4eba\u305f\u3061\u306e
\u30d3\u30bf\u30df\u30f3D\u6fc3\u5ea6\u304c\u4f4e\u3044\u306e\u306f\u3001
\u8457\u8005\u3089\u306f\u3001\u4e00\u3064\u306e\u53ef\u80fd\u6027\u3068\u3057\u3066\u3001
Long-COIVD\u60a3\u8005\u3067\u306f\u708e\u75c7\u304c\u6301\u7d9a\u3059\u308b\u3053\u3068\u3067\u3001
\u30d3\u30bf\u30df\u30f3D\u7d50\u5408\u86cb\u767d\u304c\u6d88\u8017\u3057\u3001
\u305d\u306e\u7d50\u679c25(OH)\u30d3\u30bf\u30df\u30f3D\u6fc3\u5ea6\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b
\u3068\u8003\u5bdf\u3057\u3066\u3044\u307e\u3059\u3002

\u305d\u3057\u3066\u3001\u3082\u3057\u5927\u898f\u6a21\u306a\u4ecb\u5165\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u78ba\u8a8d\u3055\u308c\u308c\u3070\u3001
\u30d3\u30bf\u30df\u30f3D\u88dc\u5145\u306fCOVID-19\u306e\u5f8c\u907a\u75c7\u306e\u8ca0\u62c5\u3092\u8efd\u6e1b\u3059\u308b
\u4e88\u9632\u6226\u7565\u306e\u53ef\u80fd\u6027\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u3068\u7de0\u3081\u304f\u304f\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u524d\u56de\u306f\u3001Long-COIVD\u3068\u8178\u5185\u306e\u771f\u83cc\u304c\u95a2\u9023\u304c\u3042\u308b\u306e\u3067\u306f\uff1f\u3068\u3044\u3046\u8a71\u3067\u3057\u305f\u304c\u3001\u4eca\u56de\u306f\u3001Long-COIVD\u3068\u30d3\u30bf\u30df\u30f3D\u3068\u306e\u95a2\u9023\u3067\u3059\u3002 \u201dLow Vitamin D Levels Are Associated With L …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[89,6],"tags":[67],"class_list":["post-9648","post","type-post","status-publish","format-standard","hentry","category-covid-19","category-blog","tag-covid-19"],"_links":{"self":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9648","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9648"}],"version-history":[{"count":3,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9648\/revisions"}],"predecessor-version":[{"id":9651,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9648\/revisions\/9651"}],"wp:attachment":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9648"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9648"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9648"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}