
{"id":9643,"date":"2023-11-24T08:28:00","date_gmt":"2023-11-23T23:28:00","guid":{"rendered":"http:\/\/www.itaya.or.jp\/?p=9643"},"modified":"2023-11-23T22:47:20","modified_gmt":"2023-11-23T13:47:20","slug":"long-covid%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8b%e8%ab%96%e6%96%871","status":"publish","type":"post","link":"https:\/\/www.itaya.or.jp\/?p=9643","title":{"rendered":"Long-COVID\u306b\u95a2\u3059\u308b\u8ad6\u65871"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u524d\u56de\u306e\u30d6\u30ed\u30b0\u6295\u7a3f\u304b\u3089\u307b\u3068\u3093\u30691\u30f6\u6708\u8fd1\u304f\u958b\u3044\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002<br>\u3068\u3073\u592a\u304f\u3093\u306e\u8a71\u3082\u307e\u3060\u307e\u3060\u66f8\u3051\u308b\u306e\u3067\u3059\u304c\u3001<br>\u305d\u308c\u3070\u304b\u308a\u3060\u3068\u904a\u3093\u3067\u3070\u304b\u308a\u3044\u308b\u69d8\u306b\u601d\u308f\u308c\u305d\u3046\u3067\u3001<br>\u3060\u304b\u3089\u3068\u8a00\u3063\u3066\u3001\u30a2\u30ab\u30c7\u30df\u30c3\u30af\u306a\u8a71\u3082\u4f55\u3068\u306a\u304f\u66f8\u3051\u306a\u304f\u3066\u3001<br>\u300c\u3042\uff5e\u3001\u66f8\u304b\u306a\u304d\u3083\u300d\u3068\u601d\u3046\u3060\u3051\u3067\u3001<br>\u30d1\u30bd\u30b3\u30f3\u306e\u524d\u306b\u5ea7\u308b\u3068\u3001\u7d50\u5c40\u9055\u3046\u3053\u3068\u3070\u304b\u308a\u3084\u3063\u3066<br>\u6642\u9593\u3070\u304b\u308a\u904e\u304e\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002<br><br>\u307e\u3001\u305d\u3046\u3044\u3046\u3053\u3068\u3082\u3042\u308b\u308f\u3044\u306a\u3002<br><br>\u3068\u306f\u8a00\u3046\u3082\u306e\u306e\u3001\u3053\u3053\u306b\u6765\u3066Long-COIVD\u306e\u8ad6\u6587\u304c<br>\u3044\u304f\u3064\u304b\u773c\u306b\u5165\u3063\u3066\u304d\u305f\u306e\u3067\u3001\u4e00\u9023\u3068\u3057\u3066\u53d6\u308a\u4e0a\u3052\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<br><br>\u307e\u305a\u306f\u300110\u670824\u65e5\u914d\u4fe1\u306enature briefing\uff1a<br>\u201d<span class=\"has-inline-color has-vivid-purple-color\">Severe COVID linked to fungal microbiome<\/span><br>An imbalance of fungi in the gut could contribute to excessive inflammation in people with severe COVID-19 or long COVID. Individuals with severe disease had elevated levels of a fungus that can activate the immune system and induce long-lasting changes. This raises the possibility that antifungal treatment could be repurposed to help people who are critically ill. It\u2019s still unclear whether this imbalance is a result of contracting COVID-19 or preceded it and made people more susceptible.\u201d<br><br>DeepL\u7c21\u6613\u7248\u3067\u8a33\uff1a<br>\u300c<span class=\"has-inline-color has-vivid-purple-color\">\u91cd\u75c7COVID\u306f\u771f\u83cc\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u3068\u95a2\u9023\u3057\u3066\u3044\u308b<\/span><br>\u91cd\u5ea6\u306eCOVID-19\u3084\u9577\u671f\u306b\u308f\u305f\u308bCOVID\u306e\u60a3\u8005\u3067\u306f\u3001\u8178\u5185\u306e\u771f\u83cc\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3001\u904e\u5270\u306a\u708e\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u91cd\u75c7\u306e\u60a3\u8005\u3067\u306f\u3001\u514d\u75ab\u7cfb\u3092\u6d3b\u6027\u5316\u3057\u3001\u9577\u671f\u306b\u308f\u305f\u308b\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u306e\u3042\u308b\u771f\u83cc\u306e\u30ec\u30d9\u30eb\u304c\u4e0a\u6607\u3057\u3066\u3044\u305f\u3002\u3053\u306e\u3053\u3068\u306f\u3001\u6297\u771f\u83cc\u6cbb\u7642\u304c\u91cd\u75c7\u60a3\u8005\u3092\u52a9\u3051\u308b\u305f\u3081\u306b\u518d\u5229\u7528\u3055\u308c\u308b\u53ef\u80fd\u6027\u3092\u63d0\u8d77\u3057\u3066\u3044\u308b\u3002\u3053\u306e\u30a2\u30f3\u30d0\u30e9\u30f3\u30b9\u304cCOVID-19\u306b\u7f79\u60a3\u3057\u305f\u7d50\u679c\u306a\u306e\u304b\u3001\u305d\u308c\u3068\u3082\u7f79\u60a3\u524d\u304b\u3089\u7f79\u60a3\u3057\u3084\u3059\u304f\u306a\u3063\u3066\u3044\u305f\u306e\u304b\u306f\u307e\u3060\u4e0d\u660e\u3067\u3042\u308b\u3002\u300d<br><br>\u30ea\u30f3\u30af\u5148\u306enature\u306e\u672c\u8a18\u4e8b\uff1a<br>\u201d<a rel=\"noreferrer noopener\" href=\"https:\/\/doi.org\/10.1038\/d41586-023-03295-w\" target=\"_blank\">Inflammation in severe COVID linked to bad fungal microbiome<\/a><br>\uff08\u91cd\u75c7COVID\u306b\u304a\u3051\u308b\u708e\u75c7\u306f\u3001\u60aa\u7389\u771f\u83cc\u306e\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\uff09\u201d<br><br>\u3053\u306e\u8a18\u4e8b\u3092\u66f8\u304f\u306b\u3042\u305f\u3063\u3066\u30a2\u30af\u30bb\u30b9\u3057\u3066\u307f\u305f\u306e\u3067\u3059\u304c\u3001<br>\u6709\u6599\u8a18\u4e8b\u306b\u306a\u3063\u3066\u307e\u3059\u306d\u3002<br>\u304a\u91d1\u6255\u3063\u3066\u8aad\u3093\u3060\u899a\u3048\u304c\u306a\u3044\u306e\u3067\u3059\u304c\u30fb\u30fb\u30fb<br>\u6642\u9593\u304c\u305f\u3063\u305f\u3089\u6709\u6599\u306b\u306a\u308b\u306e\u304b\u306a\uff1f<br>\u307e\u3042\u3001\u8aad\u3081\u308b\u4eba\u306f\u63a2\u3057\u3066\u307f\u3066\u304f\u3060\u3055\u3044\u3002<br><br>\u307e\u305f\u3001\u95a2\u9023\u6587\u732e\u3068\u3057\u3066\u3001<br><a href=\"https:\/\/www.nature.com\/articles\/s41590-023-01637-4\" target=\"_blank\" rel=\"noreferrer noopener\">\u201dFungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19<\/a><br>\uff08\u771f\u83cc\u5fae\u751f\u7269\u53e2\u306f\u91cd\u75c7COVID-19\u306b\u304a\u3051\u308b\u597d\u4e2d\u7403\u3068\u305d\u306e\u524d\u99c6\u7d30\u80de\u306e\u6301\u7d9a\u7684\u306a\u514d\u75ab\u6d3b\u6027\u5316\u3092\u7dad\u6301\u3059\u308b\uff09\u201d<br>Nature Immunologyvolume 24, pages1879?1889 (2023)<br>\u304c\u4e0a\u304c\u3063\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u3053\u3061\u3089\u306f\u7121\u6599\u3067\u8aad\u3080\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<br><br>\u8981\u306f\u3001\u8178\u5185\u306e\u904e\u5270\u306a\u300c\u771f\u83cc\u53e2\u300d\u304c<br>\u6709\u5bb3\u306a\u514d\u75ab\u53cd\u5fdc\u306e\u5f15\u304d\u91d1\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3001\u3068\u3044\u3046\u3053\u3068\u3002<br><br>\u307e\u305f\u3001SARS-CoV-2\u967d\u6027\u3068\u5224\u5b9a\u3055\u308c\u305f\u3053\u3068\u306e\u306a\u3044\u4eba\u3068\u6bd4\u8f03\u3059\u308b\u3068\u3001<br>\u91cd\u75c7\u306eCOVID-19\u60a3\u8005\u306f\u3001<br>Candida albicans\u7b49\u306e\u771f\u83cc\u306e\u6297\u4f53\u304c\u9ad8\u304b\u3063\u305f\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308b\u3068\u306e\u3053\u3068\u3002<br>\u305d\u3057\u3066\u305d\u306e\u5909\u5316\u306fLong-COVID\u306b\u4f34\u3046\u708e\u75c7\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3001<br>\u3068\u3044\u3046\u3053\u3068\u304b\u3068\u601d\u3044\u307e\u3059\u3002<br><br>\u307e\u3042\u3001\u3082\u3068\u3082\u3068\u8178\u5185\u306bC.albicans\u304c\u591a\u3044\u4eba\u304c\u3001<br>\u91cd\u75c7COVID-19\u3084Long-COIVD\u306b\u306a\u308a\u3084\u3059\u3044\u306e\u304b\u3001<br>COVID-19\u306b\u611f\u67d3\u3057\u305f\u7d50\u679c\u3001C.albicans\u304c\u5897\u3048\u305f\u4eba\u304c\u3001Long-COIVD\u306b\u306a\u308b\u306e\u304b\u3001<br>\u3064\u307e\u308a\u539f\u56e0\u306a\u306e\u304b\u7d50\u679c\u306a\u306e\u304b\u3001\u3068\u3044\u3046\u3053\u3068\u306f\u3042\u308a\u307e\u3059\u304c\u3001<br>\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u6297\u771f\u83cc\u85ac\u304c<br>Long-COIVD\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u6226\u7565\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<br><br>\u98a8\u90aa\u3067\u6297\u751f\u5264\u3068\u3044\u3046\u306e\u306f\u3001<br>\u672c\u6765\u98a8\u90aa\u306f\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306a\u306e\u3067\u5fc5\u8981\u304c\u306a\u3044\u308f\u3051\u3067\u3001<br>\u8010\u6027\u83cc\u3092\u4f5c\u3089\u306a\u3044\u305f\u3081\u306b\u3082\u4f7f\u308f\u306a\u3044\u69d8\u306b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u3001<br>\u3042\u3068\u306b\u6025\u6027\u526f\u9f3b\u8154\u708e\u306b\u306a\u3063\u305f\u308a\u3001<br>\u306e\u3069\u306e\u75db\u307f\u3092\u93ae\u75db\u5264\u3060\u3051\u3067\u3057\u306e\u3067\u3044\u305f\u4eba\u304c<br>\u6241\u6843\u5468\u56f2\u81bf\u760d\u306b\u306a\u3063\u305f\u308a\u3059\u308b\u306e\u3092\u898b\u308b\u3068\u3001<br>\u3069\u3046\u3057\u3066\u3082\u6297\u751f\u5264\u3092\u51fa\u3057\u305f\u304f\u306a\u308a\u307e\u3059\u3002<br>\u3057\u304b\u3057\u3001\u8178\u5185\u306b\u771f\u83cc\u304c\u5897\u3048\u308b\u53ef\u80fd\u6027\u3092\u8003\u3048\u308b\u3068<br>\u305d\u308c\u3082\u8003\u3048\u3082\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<br>\u60a9\u307e\u3057\u3044\u554f\u984c\u3067\u3059\u3002<br>\u7d50\u5c40\u4e00\u756a\u5927\u5207\u306a\u306e\u306f\u3001<br>\u81ea\u7136\u514d\u75ab\u3092\u3057\u3063\u304b\u308a\u3064\u3051\u3066\u304a\u304f\u3068\u3044\u3046\u3053\u3068\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<br><br>\u3068\u3001\u3053\u3053\u307e\u3067\u66f8\u3044\u3066\u601d\u3044\u51fa\u3057\u307e\u3057\u305f\u3002<br>\u5f53\u9662\u306e\u30d6\u30ed\u30b0\u3067\u3001SARS-Cov-2\u3068\u8178\u5185\u7d30\u83cc\u306b\u3064\u3044\u3066\u4f55\u5ea6\u304b\u53d6\u308a\u4e0a\u3052\u307e\u3057\u305f\u3002<br><br>\u6700\u521d\u306f\u30d7\u30ec\u30dc\u30c6\u30e9\u83cc\u304c\u95a2\u4fc2\u3059\u308b\u306e\u3067\u306f\u3068\u304b<br>\uff1e<a rel=\"noreferrer noopener\" href=\"http:\/\/www.itaya.or.jp\/?p=6933\" target=\"_blank\">\u65b0\u578b\u30b3\u30ed\u30ca\u611f\u67d3\u75c7\u3068\u30d7\u30ec\u30dc\u30c6\u30e9\u83cc?1<\/a>\uff5e4<br>\uff1e<a rel=\"noreferrer noopener\" href=\"http:\/\/www.itaya.or.jp\/?p=6927\" target=\"_blank\">\u65b0\u578b\u30b3\u30ed\u30ca\u611f\u67d3\u75c7\u3068\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30bf2<\/a><br>\uff08\u3053\u308c\u3089\u306f\u3069\u3061\u3089\u304b\u3068\u8a00\u3046\u3068\u6700\u7d42\u7684\u306b\u5426\u5b9a\u7684\u3067\u3057\u305f\uff09<br><br>\u307e\u305f\u3001\u30b3\u30ea\u30f3\u30bb\u30e9\u83cc\u3068\u3044\u3046\u306e\u304c\u3001\u9006\u306b\u91cd\u75c7\u5316\u3092\u9632\u3044\u3067\u304f\u308c\u308b\u3068\u304b<br>\uff1eS<a rel=\"noreferrer noopener\" href=\"http:\/\/www.itaya.or.jp\/?p=8160\" target=\"_blank\">ARS-Cov-2\u3068\u8178\u5185\u7d30\u83cc\uff12<\/a><br><br><br>\u8178\u5185\u306e\u5fae\u751f\u7269\u53e2\u3068\u5065\u5eb7\u306b\u3064\u3044\u3066\u306f\u307e\u3060\u307e\u3060\u3044\u308d\u3044\u308d\u3068\u51fa\u3066\u304d\u305d\u3046\u3067\u3059\u3002<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u524d\u56de\u306e\u30d6\u30ed\u30b0\u6295\u7a3f\u304b\u3089\u307b\u3068\u3093\u30691\u30f6\u6708\u8fd1\u304f\u958b\u3044\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002\u3068\u3073\u592a\u304f\u3093\u306e\u8a71\u3082\u307e\u3060\u307e\u3060\u66f8\u3051\u308b\u306e\u3067\u3059\u304c\u3001\u305d\u308c\u3070\u304b\u308a\u3060\u3068\u904a\u3093\u3067\u3070\u304b\u308a\u3044\u308b\u69d8\u306b\u601d\u308f\u308c\u305d\u3046\u3067\u3001\u3060\u304b\u3089\u3068\u8a00\u3063\u3066\u3001\u30a2\u30ab\u30c7\u30df\u30c3\u30af\u306a\u8a71\u3082\u4f55\u3068\u306a\u304f\u66f8\u3051\u306a\u304f\u3066\u3001\u300c\u3042\uff5e\u3001\u66f8\u304b\u306a\u304d\u3083\u300d &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[89,75,6],"tags":[67],"class_list":["post-9643","post","type-post","status-publish","format-standard","hentry","category-covid-19","category-75","category-blog","tag-covid-19"],"_links":{"self":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9643","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9643"}],"version-history":[{"count":3,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9643\/revisions"}],"predecessor-version":[{"id":9647,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/9643\/revisions\/9647"}],"wp:attachment":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9643"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9643"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9643"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}