{"id":9414,"date":"2023-08-09T08:28:00","date_gmt":"2023-08-08T23:28:00","guid":{"rendered":"http:\/\/www.itaya.or.jp\/?p=9414"},"modified":"2024-10-05T01:47:43","modified_gmt":"2024-10-04T16:47:43","slug":"%e6%9c%ac%ef%bc%9a%e3%83%a1%e3%83%b3%e3%82%bf%e3%83%ab%e3%82%92%e5%bc%b7%e3%81%8f%e3%81%99%e3%82%8b%e9%a3%9f%e7%bf%92%e6%85%a38%e3%80%80","status":"publish","type":"post","link":"https:\/\/www.itaya.or.jp\/?p=9414","title":{"rendered":"\u672c\uff1a\u30e1\u30f3\u30bf\u30eb\u3092\u5f37\u304f\u3059\u308b\u98df\u7fd2\u61638\u3000"},"content":{"rendered":"\n<p 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has-vivid-cyan-blue-color\">\uff1c\u30ca\u30a4\u30a2\u30b7\u30f3\u3001NMN\u3001NAD\uff0b\uff1e<\/span>p.295<br>\u30ca\u30a4\u30a2\u30b7\u30f3\uff1a\u30cb\u30b3\u30c1\u30f3\u9178\u3068\u30cb\u30b3\u30c1\u30f3\u30a2\u30df\u30c9\u306e\u7dcf\u79f0\u3001\u5225\u540d\u30d3\u30bf\u30df\u30f3B3<br><br>\u30ca\u30a4\u30a2\u30b7\u30f3\u6b20\u4e4f\uff08\u30da\u30e9\u30b0\u30e9\uff09\u30fb\u30fb\u30fb\u76ae\u819a\u708e\u3001\u4e0b\u75e2\u3001\u7cbe\u795e\u795e\u7d4c\u969c\u5bb3<br>\u30a2\u30eb\u30b3\u30fc\u30eb\u5927\u91cf\u98f2\u9152\u8005\u3001\u6975\u7aef\u306a\u504f\u98df\u306e\u4eba\u306b\u591a\u3044<br><br>\u30ca\u30a4\u30a2\u30b7\u30f3\u306f\u5c0f\u8178\u304b\u3089\u5438\u53ce\u3055\u308c\u21d2NAD\u306b\u306a\u308b\u21d2NADP\u30fb\u30fb\u30fb\u9178\u5316\u9084\u5143\u53cd\u5fdc\u306b\u95a2\u4e0e<br>\u304b\u3089\u3060\u306e\u3059\u3079\u3066\u306e\u9178\u5316\u9084\u5143\u53cd\u5fdc\u306e\uff17\u5272\u8fd1\u304f\u306b\u304a\u3044\u3066\u30ca\u30a4\u30a2\u30b7\u30f3\u304c\u88dc\u9175\u7d20<br><br>\u30a2\u30eb\u30b3\u30fc\u30eb\u5206\u89e3\u306b\u3082\u5fc5\u8981\u306a\u88dc\u9175\u7d20<br>LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3084\u4e2d\u6027\u8102\u80aa\u3092\u4e0b\u3052\u3001<br>HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4e0a\u6607\u3055\u305b\u308b\uff08\u8840\u6e05\u8102\u8cea\u6539\u5584\u4f5c\u7528\uff09<br>\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u751f\u5408\u6210\u306b\u50cd\u304f\u9175\u7d20\u306e\u88dc\u9175\u7d20<br><br>\u6b27\u7c73\u3067\u306f\u30e1\u30f3\u30bf\u30eb\u4e0d\u8abf\u306b\u30ca\u30a4\u30a2\u30b7\u30f3\u3092\u4f7f\u3046\u306e\u306f\u30dd\u30d4\u30e5\u30e9\u30fc<br>\u6700\u8fd1\u3001\u30ca\u30a4\u30a2\u30b7\u30f3\u306e\u4ee3\u8b1d\u7269\u304c\u30b5\u30fc\u30c1\u30e5\u30a4\u30f3\u907a\u4f1d\u5b50\uff08\u9577\u5bff\u907a\u4f1d\u5b50\uff09\u306b\u3082<br>\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u3067\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b<br><br>NAD\u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3001DNA\u306e\u640d\u50b7\u30fb\u4fee\u5fa9\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u3001<br>\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u3092\u5236\u5fa1\u3057\u3001\u6297\u9178\u5316\u306b\u50cd\u304f<br><br>NAD\u3092\u5897\u3084\u3059\u306b\u306f\u4e00\u3064\u624b\u524d\u306eNMN\uff08\u30cb\u30b3\u30c1\u30f3\u30a2\u30df\u30c9\u30fb\u30e2\u30ce\u30fb\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\uff09\u3092<br>\u88dc\u5145\u3059\u308b\u306e\u304c\u3088\u3044<br>\u305f\u3060\u73fe\u72b6\u3067\u306f\u975e\u5e38\u306b\u9ad8\u4fa1<br><br><span 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has-vivid-cyan-blue-color\">\uff1c\u30d3\u30bf\u30df\u30f3A\uff1e<\/span>\u3000p.302<br>\u8102\u6eb6\u6027\u30d3\u30bf\u30df\u30f3<br>\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u3068\u540c\u69d8\u3001\u6838\u5185\u53d7\u5bb9\u4f53\u306b\u52b9\u304f\u305f\u3081\u3001\u901f\u3084\u304b\u306b\u92ed\u3044\u52b9\u304d\u65b9\u3092\u3059\u308b<br>\u81ea\u9589\u75c7\u3084\u767a\u9054\u969c\u5bb3\u306e\u60a3\u8005\u3055\u3093\u306b\u6804\u990a\u7642\u6cd5\u3092\u884c\u3046\u3068\u304d\u306f\u30d3\u30bf\u30df\u30f3A\u3092\u6442\u3063\u3066\u3082\u3089\u3046<br>\u4e9c\u925b\u4e0d\u8db3\u3060\u3068\u30d3\u30bf\u30df\u30f3A\u304c\u5341\u5206\u50cd\u3051\u306a\u3044\u305f\u3081\u4e9c\u925b\u3082\u540c\u6642\u306b\u88dc\u5145\u3057\u3066\u3082\u3089\u3046<br><br>\u76ae\u819a\u3084\u7c98\u819c\u306e\u5065\u5eb7\u306b\u5927\u304d\u304f\u95a2\u4e0e<br>\u76ae\u819a\u3001\u53e3\u3001\u547c\u5438\u5668\u3001\u6d88\u5316\u5668\u306a\u3069\u3001\u5168\u8eab\u306e\u7c98\u819c\u3092\u5065\u5eb7\u306b\u4fdd\u3064\u305f\u3081\u306b\u5fc5\u8981<br>\u21d2\u514d\u75ab\u306b\u3082\u95a2\u4e0e\uff1aIgA\u30fb\u30fb\u30fb\u4f4e\u4e0b\u3059\u308b\u3068\u98a8\u90aa\u3092\u3072\u304d\u3084\u3059\u304f\u306a\u308b<br>\u21d2 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class=\"has-inline-color has-vivid-cyan-blue-color\">\uff1c\u30d3\u30bf\u30df\u30f3C\uff1e<\/span>\u3000p.305<br>\u6bd2\u866b\u306b\u523a\u3055\u308c\u305f\u308a\u3059\u308b\u3068\u3001<br>\u30d3\u30bf\u30df\u30f3C\u306e\u8840\u4e2d\u6fc3\u5ea6\u304c\u691c\u51fa\u9650\u754c\u4ee5\u4e0b\u306b\u306a\u308b\u307b\u3069\u6d88\u8017\u304c\u8d77\u3053\u308b<br><br>\u6297\u9178\u5316\u7269\u3068\u3057\u3066\u50cd\u304f\u3068\u304d\u3001\u30d3\u30bf\u30df\u30f3C\uff54\u30d3\u30bf\u30df\u30f3\uff25\u306f\u30bb\u30c3\u30c8\u3067\u50cd\u304f<br>\u30d3\u30bf\u30df\u30f3\uff23\u306f\u3001\u30d3\u30bf\u30df\u30f3\uff25\u30fb\u5c3f\u9178\u30fb\u30b0\u30eb\u30bf\u30c1\u30aa\u30f3\u30fb\u03b2\u30ab\u30ed\u30c6\u30f3\u3068\u3044\u3063\u305f<br>\u6297\u9178\u5316\u7269\u304c\u50cd\u3044\u3066\u81ea\u3089\u304c\u9178\u5316\u3057\u305f\u3068\u304d\u306b\u3001\u305d\u308c\u3092\u9084\u5143\u3057\u3066\u518d\u751f\u3092\u56f3\u308b<br><br>\u708e\u75c7\u304c\u3042\u308b\u3068\u597d\u4e2d\u7403\u304c\u6d3b\u6027\u5316\u3057\u3001\u6b21\u4e9c\u5869\u7d20\u9178\u3092\u51fa\u3057\u3066\u6bba\u83cc\u3057\u3088\u3046\u3068\u3059\u308b<br>\u3057\u304b\u3057\u6b21\u4e9c\u5869\u7d20\u9178\u306e\u904e\u5270\u767a\u751f\u306f\u7d44\u7e54\u3092\u58ca\u3057\u3066\u3057\u307e\u3046<br>\u30d3\u30bf\u30df\u30f3\uff23\u306f\u6b21\u4e9c\u5869\u7d20\u9178\u306b\u3088\u308b\u9178\u5316\u3092\u6b62\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u3001<br>\u3072\u3069\u3044\u708e\u75c7\u304c\u3042\u308b\u3068\u304d\u306f\u3001\u30d3\u30bf\u30df\u30f3\uff23\u3092\u6442\u308b\u3053\u3068\u306f\u975e\u5e38\u306b\u6709\u7528<br><br>\u30d3\u30bf\u30df\u30f3\uff23\u6b20\u4e4f\u30fb\u30fb\u30fb\u58ca\u8840\u75c5<br>\u4eca\u306f\u9ad8\u9f62\u8005\u3067\u30d7\u30c1\u58ca\u8840\u75c5\u304c\u3044\u308b\u30fb\u30fb\u30fb\u8840\u7ba1\u304c\u3082\u308d\u3044<br>\u30b3\u30e9\u30fc\u30b2\u30f3\u306f\u3001\u9244\u30fb\u30bf\u30f3\u30d1\u30af\u30fb\u30d3\u30bf\u30df\u30f3\uff23\u304b\u3089\u5408\u6210\u3055\u308c\u308b<br>\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\u306e\u4f4e\u4e0b\u306f\u3001\u82e5\u3044\u5973\u6027\u306e\u5834\u5408\u9244\u4e0d\u8db3\u3001<br>\u9ad8\u9f62\u8005\u306e\u5834\u5408\u30d3\u30bf\u30df\u30f3C\u4e0d\u8db3\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u3044<br><br>\u809d\u81d3\u3067\u306e\u89e3\u6bd2\u306b\u304b\u304b\u308f\u308b\u30b7\u30c8\u30af\u30ed\u30e0P450\u306e\u6a5f\u80fd\u7dad\u6301\u306b\u306f\u30d3\u30bf\u30df\u30f3C\u304c\u5fc5\u8981<br>\u30d3\u30bf\u30df\u30f3C\u4e0d\u8db3\u3060\u3068\u89e3\u6bd2\u304c\u3046\u307e\u304f\u3044\u304b\u306a\u3044<br>\u85ac\u306e\u8840\u4e2d\u6fc3\u5ea6\u304c\u4e0a\u304c\u308a\u3001\u526f\u4f5c\u7528\u304c\u51fa\u3084\u3059\u3044<br><br>\u30d3\u30bf\u30df\u30f3C\u3082\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3057\u3066\u3082\u3068\u308c\u3082\u91cd\u8981\u306a\u6804\u990a\u7d20<br>\u30c9\u30fc\u30d1\u30df\u30f3\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u3001\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306a\u3069<br>\u9ad8\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u7523\u751f\u5206\u6ccc\u306b\u95a2\u4e0e<br><br>\u30d3\u30bf\u30df\u30f3C\u4e0d\u8db3\u3059\u308b\u3068\u3001\u6162\u6027\u75b2\u52b4\u3001\u9ad8\u8102\u8840\u75c7\u3001\u80a5\u6e80\u306b\u3064\u306a\u304c\u308b<br>\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304b\u3089\u80c6\u6c41\u9178\u3092\u3064\u304f\u308b\u306e\u306b\u30d3\u30bf\u30df\u30f3C\u304c\u5927\u91cf\u306b\u5fc5\u8981<br>\u4eba\u9593\u306e\u4f53\u5185\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u534a\u5206\u4ee5\u4e0a\u304c\u80c6\u6c41\u9178\u306e\u751f\u6210\u306b\u4f7f\u308f\u308c\u308b<br>\u30d3\u30bf\u30df\u30f3C\u304c\u4e0d\u8db3\u3059\u308b\u3068\u3001\u80c6\u6c41\u9178\u304c\u3064\u304f\u3089\u308c\u306a\u304f\u306a\u308a\u3001<br>\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f59\u308b\u306e\u3067\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7<br><br>\u30d3\u30bf\u30df\u30f3C\u306f\u30d2\u30b9\u30bf\u30df\u30f3\u3092\u6291\u3048\u308b\u4f5c\u7528\u3082\u3042\u308b\u30fb\u30fb\u30fb\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306e\u4e88\u9632\u30fb\u6cbb\u7642\u306b\u6709\u7528<br>\u76ee\u306e\u6c34\u6676\u4f53\u306f\u900f\u660e\u6027\u3092\u4fdd\u3064\u305f\u3081\u306b\u30d3\u30bf\u30df\u30f3C\u304c\u5fc5\u8981\u30fb\u30fb\u30fb\u4e0d\u8db3\u3059\u308b\u3068\u767d\u5185\u969c\u306b<br>\u795e\u7d4c\u7d30\u80de\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u304b\u3089\u5b88\u308b\u30fb\u30fb\u30fb\u8133\u306b\u304a\u3044\u3066\u3082\u91cd\u8981\u306a\u6804\u990a\u7d20<br>\u30d5\u30ea\u30fc\u30e9\u30b8\u30ab\u30eb\u3092\u53d6\u308a\u9664\u304d\u3001\u514d\u75ab\u3092\u5f37\u5316\u3059\u308b<br>\u5927\u91cf\u6442\u53d6\u3067\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642<br><br>\u305d\u306e\u4ed6\u3001\u5fc3\u81d3\u75c5\u3001\u80ba\u708e\u3001\u8133\u708e\u3001\u304c\u3093\u3001\u5e2f\u72b6\u75b1\u75b9\u3001\u95a2\u7bc0\u708e\u3001\u52d5\u8108\u786c\u5316\u3001<br>\u690e\u9593\u677f\u30d8\u30eb\u30cb\u30a2\u3001\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u7cd6\u5c3f\u75c5\u3001\u7d71\u5408\u5931\u8abf\u75c7\u3001<br>\u591a\u767a\u6027\u786c\u5316\u75c7\u3001\u6162\u6027\u75b2\u52b4\u306a\u3069<br>30\u4ee5\u4e0a\u306e\u91cd\u5927\u75be\u60a3\u306b\u6709\u52b9\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u308b<br><br>\u30d3\u30bf\u30df\u30f3C\u306f\u6c34\u306b\u6eb6\u3044\u305f\u3089\u3059\u3050\u9178\u5316\u3057\u3066\u3057\u307e\u3046\u306e\u3067\u3001\u6eb6\u3044\u305f\u3089\u3059\u3050\u98f2\u3080<br>\u8272\u3064\u304d\u306e\u91ce\u83dc\u304b\u3089\u6442\u53d6<br>\u30d6\u30ed\u30c3\u30b3\u30ea\u30fc\u3001\u30ab\u30ea\u30d5\u30e9\u30ef\u30fc\u3001\u307b\u3046\u308c\u3093\u8349\u3001\u30ad\u30e3\u30d9\u30c4\u3001\u30ec\u30e2\u30f3\u3001\u30ab\u30d6\u3001\u30cd\u30ae\u306a\u3069<br><br><span class=\"has-inline-color has-vivid-cyan-blue-color\">\uff1c\u30d3\u30bf\u30df\u30f3E\uff1e<\/span>\u3000p.313<br>\u6297\u4e0d\u598a\u56e0\u5b50\u3068\u3057\u3066\u767a\u898b\u3055\u308c\u305f<br>\u30d3\u30bf\u30df\u30f3C\u3068\u9023\u643a\u3057\u306a\u304c\u3089\u304a\u4e92\u3044\u3092\u30ea\u30b5\u30a4\u30af\u30eb\u3059\u308b\u4ee3\u8868\u7684\u306a\u6297\u9178\u5316\u5264<br>\u4e0d\u8db3\u3059\u308b\u3068\u7d30\u80de\u819c\u304c\u58ca\u308c\u3084\u3059\u304f\u306a\u308b<br>\u8d64\u8840\u7403\uff1a\u6eb6\u8840\u3057\u3084\u3059\u304f\u306a\u308b<br><br>\u5185\u5206\u6ccc\u3001\u7b4b\u8089\u3001\u672b\u68a2\u8840\u7ba1\u7cfb\u306e\u6210\u9577\u306b\u6b20\u304b\u305b\u306a\u3044<br>\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u306e\u9178\u5316\u3092\u9632\u6b62<br>\u8840\u6813\u3092\u6eb6\u304b\u3057\u305f\u308a\u3001\u5074\u526f\u8840\u884c\u8def\u3092\u6539\u5584\u3057\u305f\u308a\u3001\u6bdb\u7d30\u8840\u7ba1\u3092\u4fdd\u8b77\u3057\u305f\u308a\u3059\u308b<br><br>\u30d3\u30bf\u30df\u30f3E\u4e0d\u8db3\u30fb\u30fb\u30fb\u30ea\u30a6\u30de\u30c1\u3001\u9593\u6b20\u6027\u8ddb\u884c\u3001\u809d\u786c\u5909\u3001\u6025\u6027\u814e\u708e\u3001\u7db2\u819c\u708e\u306a\u3069<br><br><span class=\"has-inline-color has-vivid-cyan-blue-color\">\uff1c\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\uff1e<\/span>\u3000p.315<br>\u6297\u9178\u5316\u4f5c\u7528\u306e\u6804\u990a\u7d20\u3068\u7d50\u8a17\u3057\u3066\u6d3b\u6027\u9178\u7d20\u304b\u3089\u5b88\u308b<br>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u96fb\u5b50\u4f1d\u9054\u7cfb\u3067\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3059<br>\u5fc3\u81d3\u306f\u5e38\u306b\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u7523\u751f\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u81d3\u5668\u306a\u306e\u3067\u9ad8\u6fc3\u5ea6\u3067\u5b58\u5728<br><br><span class=\"has-inline-color has-vivid-cyan-blue-color\">\uff1c5\uff0dALA\uff085\u30fc\u30a2\u30df\u30ce\u30ec\u30d6\u30ea\u30f3\u9178\uff09\uff1e<\/span>p.316<br>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u304c\u4f5c\u3063\u3066\u3044\u308b\u30a2\u30df\u30ce\u9178<br>COVID-19\u306b\u5bfe\u3059\u308b\u4e88\u9632\u52b9\u679c\u304c\u3042\u308b\u3068\u8a71\u984c\u306b\u306a\u3063\u305f<br>\u75b2\u52b4\u611f\u306e\u8efd\u6e1b\u3001\u8840\u7cd6\u5024\u306e\u6539\u5584\u3001\u904b\u52d5\u6a5f\u80fd\u306e\u4e0a\u6607\u3001<br>\u7761\u7720\u306e\u8cea\u5411\u4e0a\u3001\u808c\u306e\u6c34\u5206\u91cf\u3084\u5f3e\u529b\u6027\u30a2\u30c3\u30d7<br><br>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3067\u4f5c\u3089\u308c\u3001\u7d30\u80de\u8cea\u306b\u9001\u308a\u51fa\u3055\u308c\u3066\u30012\u3064\u304c\u7e2e\u5408\u3057\u30dd\u30eb\u30d5\u30a3\u30ea\u30f3\u3068\u306a\u308a\u3001<br>\u3082\u3046\u4e00\u5ea6\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u5f15\u304d\u8fbc\u307e\u308c\u30d8\u30e0\u306b\u5909\u63db\u3055\u308c\u3001<br>\u3055\u3089\u306b\u30b7\u30c8\u30af\u30ed\u30e0\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u69cb\u6210<br>\u6709\u6a5f\u7269\u3068\u9178\u7d20\u3067\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u4e8c\u9178\u5316\u70ad\u7d20\u3092\u751f\u307f\u51fa\u3059<br>\u751f\u547d\u306e\u6839\u6e90\u7269\u8cea<br><br><span class=\"has-inline-color has-vivid-cyan-blue-color\">\uff1c\u30d3\u30bf\u30df\u30f3D\uff1e<\/span>\u3000p.318<br>\u30d3\u30bf\u30df\u30f3A\u540c\u69d8\u6838\u5185\u53d7\u5bb9\u4f53\u306b\u76f4\u63a5\u4f5c\u7528\u3057\u3066<br>\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u306e\u69d8\u306b\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b<br>\u7c98\u819c\u72b6\u614b\u3092\u6539\u5584\u3059\u308b<br>\u5598\u606f\u3084\u30ea\u30fc\u30ad\u30fc\u30ac\u30c3\u30c8\u75c7\u5019\u7fa4\u5bfe\u7b56\u3001<br>\u82b1\u7c89\u75c7\u3084\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3001<br>\u611f\u67d3\u75c7\u4e88\u9632\u3001\u304c\u3093\u306e\u518d\u767a\u4e88\u9632\u3001\u4e0d\u598a\u3001\u81ea\u9589\u75c7\u3001\u7cd6\u5c3f\u75c5\u3001\u52d5\u8108\u786c\u5316\u306a\u3069<br>\u3055\u307e\u3056\u307e\u306a\u75c7\u72b6\u3078\u306e\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u308b<br><br>\u30d3\u30bf\u30df\u30f3D\u306e\u30b5\u30d7\u30ea\u3092\u98f2\u3093\u3067\u3082\u3089\u3046\u3068\u3001<br>\u6570\u65e5\u3067\u82b1\u7c89\u75c7\u306e\u9f3b\u708e\u75c7\u72b6\u304c\u6b62\u307e\u3063\u3066\u3057\u307e\u3046\u4eba\u304c\u3044\u308b<br>\u30d3\u30bf\u30df\u30f3D\u3067\u3051\u3067\u6b62\u307e\u3089\u306a\u3044\u4eba\u306f\u4e73\u9178\u83cc\u88fd\u5264\u3092\u7d44\u307f\u5408\u308f\u3059\u3068\u3066\u3082\u3088\u304f\u52b9\u304f\u3053\u3068\u304c\u3042\u308b<br><br>\u30d3\u30bf\u30df\u30f3D\u3084\u4e9c\u925b\u306f\u30a6\u30a4\u30eb\u30b9\u3084\u7d30\u83cc\u304c\u4eba\u306e\u7c98\u819c\u7d30\u80de\u306b\u5165\u308a\u8fbc\u3080\u306e\u3092<br>\u30d6\u30ed\u30c3\u30af\u3059\u308b\u6297\u83cc\u30fb\u6297\u30a6\u30a4\u30eb\u30b9\u30da\u30d7\u30c1\u30c9\u3092\u5897\u52a0\u3055\u305b\u308b<br><br>\u30d3\u30bf\u30df\u30f3D\u6b20\u4e4f\u3068\u3046\u3064\u75c5\u3068\u306e\u9593\u306b\u95a2\u9023\u304c\u3042\u308b\u3068\u306e\u5831\u544a\u304c\u591a\u3044<br>\u8133\u306e\u795e\u7d4c\u7d30\u80de\u306b\u306f\u30d3\u30bf\u30df\u30f3D\u306e\u53d7\u5bb9\u4f53\u304c\u591a\u304f\u5b58\u5728\u3059\u308b<br>\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\uff08\u30c9\u30fc\u30d1\u30df\u30f3\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306a\u3069\uff09\u306e\u50cd\u304d\u3092\u6539\u5584\u3055\u305b\u3066\u3044\u308b<br>\uff08\u3068\u3044\u3063\u3066\u3082\u30d3\u30bf\u30df\u30f3D\u3092\u6295\u4e0e\u3059\u308c\u3070\u3046\u3064\u75c5\u304c\u6cbb\u308a\u3068\u3044\u3046\u5358\u7d14\u306a\u8005\u3067\u3082\u306a\u3044\uff09<br>\u30d3\u30bf\u30df\u30f3D\u6295\u4e0e\u3067\u8010\u3048\u308b\u529b\u304c\u4e0a\u304c\u308b\u611f\u3058\u304c\u3059\u308b\u3068\u3044\u3046\u60a3\u8005\u3055\u3093\u304c\u6642\u3005\u3044\u308b<br><br>\u65e5\u5149\u3092\u6d74\u3073\u308b\u3068\u30d3\u30bf\u30df\u30f3D\u306f\u4e0a\u6607\u3059\u308b<br>\u30d3\u30bf\u30df\u30f3D\u304c\u4e0d\u8db3\u3059\u308b\u3068\u30ab\u30eb\u30b7\u30a6\u30e0\u306e\u5438\u53ce\u7387\u304c\u4f4e\u4e0b\u21d2\u9aa8\u8edf\u5316\u75c7<br><br><span class=\"has-inline-color has-vivid-cyan-blue-color\">\uff1c\u9244\u304c\u4e0d\u8db3\u3057\u304c\u3061\u306a\u73fe\u4ee3\u4eba\uff1e<\/span>p.274\u30fbp.322<br>\u9244\uff1a<br>\u4f53\u5185\u306b\u9178\u7d20\u3092\u904b\u3076\u3001\u8d64\u8840\u7403\u3092\u3064\u304f\u308b\u3001\u76ae\u819a\u30fb\u9aa8\u30fb\u7c98\u819c\u306e\u4ee3\u8b1d\u306b\u50cd\u304f\u3001<br>\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u6574\u5408\u6027\u306b\u50cd\u304f<br>\u9244\u304c\u306a\u3051\u308c\u3070\u30a8\u30cd\u30eb\u30ae\u30fc\u5408\u6210\u304c\u3067\u304d\u305a\u3001\u9178\u7d20\u3082\u904b\u3070\u308c\u306a\u3044<br><br>\u9244\u4e0d\u8db3\uff1a<br>\u305f\u3061\u304f\u3089\u307f\u3001\u95a2\u7bc0\u75db\u3001\u75b2\u308c\u3084\u3059\u3044\u3001\u304f\u3057\u3083\u307f\u30fb\u9f3b\u6c34\u30fb\u9f3b\u3065\u307e\u308a\u3001\u8033\u9cf4\u308a\u3001<br>\u306e\u3069\u306e\u9055\u548c\u611f\u3001\u982d\u91cd\u3001\u9aea\u304c\u629c\u3051\u3084\u3059\u3044\u3001\u51b7\u3048\u3001\u98df\u6b32\u4e0d\u632f\u3001<br>\u795e\u7d4c\u904e\u654f\u3001\u6ce8\u610f\u529b\u4f4e\u4e0b\u30fb\u3044\u3089\u3044\u3089\u3001\u5bdd\u8d77\u304d\u304c\u60aa\u3044\u3001<br>\u3042\u3056\u304c\u3067\u304d\u3084\u3059\u3044\u3001\u3080\u304f\u307f\u3001\u808c\u8352\u308c\u3001\u722a\u304c\u5272\u308c\u3084\u3059\u3044\u3001\u4fbf\u79d8\u3084\u4e0b\u75e2\u3001\u5410\u304d\u6c17\u3001<br>\u983b\u8108\u3001\u52d5\u60b8\u30fb\u606f\u5207\u308c\u3001\u591c\u4e2d\u306b\u76ee\u3092\u899a\u307e\u3059\u306a\u3069<br>\u2193<br>\u7acb\u3061\u304f\u3089\u307f\u3084\u306e\u3069\u306e\u9055\u548c\u611f\u3001\u51b7\u3048\u3001\u52d5\u60b8\u3042\u305f\u308a\u306f\u3059\u3050\u306b\u601d\u3044\u3064\u304d\u307e\u3059\u304c\u3001<br>\u9f3b\u708e\u306e\u75c7\u72b6\u306a\u3093\u304b\u306f\u3061\u3087\u3063\u3068\u95a2\u9023\u3065\u3051\u3066\u306f\u601d\u3044\u3064\u304d\u307e\u305b\u3093\u306d\u3002<br><br>\u96a0\u308c\u8ca7\u8840\u30fb\u30fb\u30fb\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u306e\u6570\u5024\u304c\u4e0b\u304c\u3063\u3066\u3044\u306a\u3044\u8ca7\u8840<br>\u8caf\u8535\u9244\u306e\u30d5\u30a7\u30ea\u30c1\u30f3\u3084MCV\u306a\u3069\u3082\u30c1\u30a7\u30c3\u30af<br><br>\u9244\u30fb\u30fb\u30fb\u8133\u3084\u904b\u52d5\u6a5f\u80fd\u306e\u767a\u9054<br>\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\uff08\u30bb\u30ed\u30c8\u30cb\u30f3\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306a\u3069\uff09\u306e\u5408\u6210\u306b\u5fc5\u8981<br>\uff08\u4ed6\u306b\u30d3\u30bf\u30df\u30f3B\u7fa4\u3082\u5fc5\u8981\uff09<br>\u7b4b\u8089\u30fb\u30fb\u30fbFe\u2193\u3060\u3068\u3068\u306b\u304b\u304f\u3060\u308b\u304f\u3066\u5143\u6c17\u304c\u3067\u306a\u3044<br>\u76ae\u819a\u30fb\u30fb\u30fb\u4e73\u5150\u6e7f\u75b9\u3001\u30a2\u30c8\u30d4\u30fc\u3082\u9244\u3084\u4e9c\u925b\u4e0d\u8db3\u3067\u306a\u308a\u3084\u3059\u3044<br>\u6bdb\u9aea\u30fb\u30fb\u30fb\u51fa\u7523\u76f4\u5f8c\u306b\u304a\u6bcd\u3055\u3093\u306e\u9aea\u306e\u6bdb\u304c\u629c\u3051\u3084\u3059\u3044<br>\u30b3\u30e9\u30fc\u30b2\u30f3\u30fb\u30fb\u8840\u7ba1\u30fb\u76ae\u819a\u30fb\u8171\u306a\u3069\uff1a\u30d3\u30bf\u30df\u30f3C\u30fb\u9244\u30fb\u30d7\u30ed\u30c6\u30a4\u30f3<br>\u6e1b\u5c11\u3059\u308b\u3068\u5185\u51fa\u8840\u3084\u8171\u306e\u30c8\u30e9\u30d6\u30eb<br><br>\u9244\u4e0d\u8db3\u3068\u805e\u3044\u3066\u3072\u3058\u304d\u30fb\u30d7\u30eb\u30fc\u30f3\u3092\u5927\u91cf\u306b\u6442\u308b\u306e\u306f\u9593\u9055\u3044<br>\u3072\u3058\u304d\u306f\u30d2\u7d20\u304c\u542b\u307e\u308c\u308b<br>\u30d7\u30eb\u30fc\u30f3\u306f\u78ba\u304b\u306b\u9244\u304c\u591a\u304f\u542b\u307e\u308c\u308b\u304c\u3001<br>\u9244\u3092\u304f\u308b\u3093\u3067\u3044\u308b\u7269\u8cea\u3092\u4eba\u9593\u306f\u6d88\u5316\u3067\u304d\u306a\u3044<br><br>\u5fc3\u7642\u5185\u79d1\u3092\u53d7\u8a3a\u3059\u308b\u60a3\u8005\u306e\u4e2d\u306b\u306f\uff08\u7279\u306b\u5973\u6027\uff09\u3001<br>\u9244\u30fb\u30bf\u30f3\u30d1\u30af\u8cea\u30fb\u30d3\u30bf\u30df\u30f3B\u7fa4\u306e\u6442\u53d6\u3060\u3051\u3067\u3082\u826f\u304f\u306a\u308b\u5834\u5408\u304c\u3042\u308b<br><br><span class=\"has-inline-color has-vivid-cyan-blue-color\">\uff1c\u4e9c\u925b\uff1e<\/span>\u3000p.325<br>\u9244\u306b\u6b21\u3044\u3067\u4f53\u5185\u306b\u591a\u3044\u5fae\u91cf\u30df\u30cd\u30e9\u30eb<br>\u524d\u7acb\u817a\u3001\u9aa8\u3001\u9aa8\u9ac4\u3001\u76ee\u306e\u8108\u7d61\u819c\u3001\u7b4b\u8089\u3001\u76ae\u819a\u306b\u591a\u304f\u5b58\u5728<br>\u4e9c\u925b\u306fDNA\u3068\u7d50\u5408\u3057\u3066\u907a\u4f1d\u5b50\u8abf\u7bc0\u3092\u3059\u308b\u6570\u591a\u304f\u306e\u9175\u7d20\u306e\u6d3b\u6027\u4e2d\u5fc3\u3068\u306a\u3063\u3066\u3044\u308b<br>\u65b0\u3057\u3044\u7d30\u80de\u3092\u4f5c\u308b\u3068\u3053\u308d\u306b\u591a\u304f\u5b58\u5728<br>\u5473\u899a\u969c\u5bb3\u30fb\u30fb\u30fb\u5473\u857e\u306e\u30bf\u30fc\u30f3\u30aa\u30fc\u30d0\u30fc\u304c\u3046\u307e\u304f\u3044\u304b\u306a\u3044\u305f\u3081\u306b\u751f\u3058\u308b<br><br>COVID-19\u306b\u3088\u308b\u5473\u899a\u30fb\u55c5\u899a\u969c\u5bb3<br>\u30a6\u30a4\u30eb\u30b9\u306b\u3088\u308b\u76f4\u63a5\u7684\u306a\u795e\u7d4c\u306e\u30c0\u30e1\u30fc\u30b8\u306e\u4ed6\u306b<br>\u611f\u67d3\u75c7\u6025\u6027\u671f\u306b\u306f\u809d\u81d3\u3067\u306e\u30a2\u30df\u30ce\u9178\u306e\u53d6\u308a\u8fbc\u304c\u5897\u3048\u308b\u305f\u3081\u3001<br>\u30a2\u30df\u30ce\u9178\u3068\u4e9c\u925b\u304c\u7d50\u5408\u3057\u809d\u81d3\u306b\u53d6\u308a\u8fbc\u307e\u308c\u3001\u8840\u4e2d\u306e\u4e9c\u925b\u304c\u6e1b\u5c11\u3059\u308b<br><br>\u4e9c\u925b\u306f\u30d3\u30bf\u30df\u30f3C\u30fb\u30d3\u30bf\u30df\u30f3D\u3068\u306a\u3089\u3073\u611f\u67d3\u4e88\u9632\u306e\u4ee3\u8868\u7684\u306a\u6804\u990a\u7d20<br>\u4e9c\u925b\u304c\u4e0d\u8db3\u3059\u308b\u3068\u30a6\u30a4\u30eb\u30b9\u306b\u5bfe\u5fdc\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u3046\u307e\u304f\u50cd\u304b\u306a\u304f\u306a\u308b<br>T\u30ea\u30f3\u30d1\u7403\u3068B\u30ea\u30f3\u30d1\u7403\u306e\u6a5f\u80fd\u4f4e\u4e0b<br>\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u7523\u751f\u306e\u4f4e\u4e0b<br>RNA\u30a6\u30a4\u30eb\u30b9\u3092\u8907\u88fd\u3059\u308b\u9175\u7d20\u3092\u963b\u5bb3<br><br>\u80a5\u6e80\u3001\u7cd6\u5c3f\u75c5\u3001\u9ad8\u9f62\u8005\u306a\u3069COVID-19\u30cf\u30a4\u30ea\u30b9\u30af\u8005\u3067<br>\u30d3\u30bf\u30df\u30f3D\u3084\u4e9c\u925b\u304c\u4e0d\u8db3\u3057\u3066\u3044\u308b<br><br>\u4e9c\u925b\u4e0d\u8db3\uff1a<br>\u514d\u75ab\u529b\u304c\u4f4e\u4e0b\u3057\u3001\u7d30\u80de\u306e\u518d\u751f\u304c\u9045\u304f\u306a\u308b<br>\u866b\u523a\u3055\u308c\u306e\u3042\u3068\u3084\u50b7\u304c\u6cbb\u308a\u306b\u304f\u3044\u3001\u3055\u3055\u304f\u308c\u306a\u3069\u808c\u306e\u30c8\u30e9\u30d6\u30eb\u3001<br>\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3001\u76ae\u819a\u63bb\u75d2\u75c7\u306a\u3069<br>\u7537\u6027\u4e0d\u598a\uff08\u9759\u6b62\u306e\u904b\u52d5\u6027\uff09<br>\u6210\u9577\u671f\u306b\u306f\u4e9c\u925b\u306e\u5fc5\u8981\u91cf\u304c\u591a\u304f\u306a\u308b<br>\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u306b\u3082\u591a\u304f\u5b58\u5728\uff1d\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5408\u6210\u30fb\u5206\u6ccc\u306b\u95a2\u4e0e<br>\u30a4\u30f3\u30b9\u30ea\u30f3\u306b\u4e9c\u925b\u304c\u7d50\u5408\u3059\u308b\u3068\u5206\u89e3\u3055\u308c\u306b\u304f\u304f\u3082\u306a\u308b<br>\u4e0b\u5782\u4f53\u306eLH\u3001FSH\u3001GH\u3001TRH\u306a\u3069\u306e\u5206\u6ccc\u306b\u3082\u95a2\u4e0e\u30fb\u30fb\u30fb\u4e0b\u5782\u4f53\u6a5f\u80fd\u4f4e\u4e0b<br>\u8996\u91ce\u30fb\u8996\u529b\u969c\u5bb3\u3001\u98df\u6b32\u4e0d\u632f\u3001\u4f53\u91cd\u6e1b\u5c11\u3001\u91cd\u5ea6\u306e\u5026\u6020\u611f\u306a\u3069<br><br><span class=\"has-inline-color has-vivid-cyan-blue-color\">\uff1c\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\uff1e<\/span>\u3000p.330<br>\u30a8\u30cd\u30eb\u30ae\u30fc\u6d3b\u52d5\u306e\u5834\u306b\u591a\u304f\u5b58\u5728\uff08\u7d0460\uff05\u306f\u9aa8\u3001\u7d0427\uff05\u306f\u7b4b\u8089\uff09<br>\u591a\u304f\u306e\u88dc\u9175\u7d20\u3068\u3057\u3066ATP\u7523\u751f\u306b\u95a2\u4e0e<br>\u30d3\u30bf\u30df\u30f3B1\u3068\u9023\u643a\u3059\u308b\u3053\u3068\u304c\u591a\u3044\u306e\u3067\u3001<br>\u4e0d\u8db3\u3059\u308b\u3068\u30d3\u30bf\u30df\u30f3B1\u4e0d\u8db3\u3068\u4f3c\u305f\u75c7\u72b6\u304c\u73fe\u308c\u308b<br><br>\u7d30\u80de\u5185\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u6fc3\u5ea6\u3092\u4f4e\u304f\u4fdd\u3064\u306e\u306b\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u304c\u5fc5\u8981<br>\u30ab\u30eb\u30b7\u30a6\u30e0\u3092\u6442\u53d6\u3059\u308b\u3068\u304d\u306b\u306f\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u3082\u30d0\u30e9\u30f3\u30b9\u826f\u304f\u6442\u308b\u5fc5\u8981\u304c\u3042\u308b<br><br>\u52a0\u5de5\u98df\u54c1\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u3001\u30b9\u30c8\u30ec\u30b9\u306a\u3069\u3067\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u306f\u5c3f\u4e2d\u306b\u6392\u6cc4\u3055\u308c\u3084\u3059\u3044<br>\u73fe\u4ee3\u4eba\u306f\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u4e0d\u8db3\u306b\u306a\u308a\u3084\u3059\u3044<br>\u6d77\u7523\u7269\u3001\u6d77\u85fb\u3092\u3042\u307e\u308a\u98df\u3079\u306a\u304f\u306a\u3063\u305f\u3053\u3068<br>\u8c46\u8150\u306e\u30cb\u30ac\u30ea\u3082\u4ed6\u306e\u51dd\u56fa\u5264\u306b\u3088\u308b\u3082\u306e\u304c\u591a\u304f\u306a\u3063\u305f<br><br>\u7d30\u80de\u5185\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u6fc3\u5ea6\u4e0a\u6607<br>\u21d2\u8840\u7ba1\u3084\u7b4b\u8089\u304c\u53ce\u7e2e\u21d2\u3053\u3080\u3089\u8fd4\u308a\u3001\u4e0d\u6574\u8108<br>\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u306b\u3088\u3063\u3066\u3053\u308c\u3089\u306e\u75c7\u72b6\u304c\u6cbb\u307e\u308b<br>\u8840\u5727\u304c\u4e0b\u304c\u308a\u3001\u80a9\u3053\u308a\u3001\u982d\u75db\u3001\u7247\u982d\u75db\u3001\u6c17\u7ba1\u652f\u5e73\u6ed1\u7b4b\u306e\u5f1b\u7de9<br>\u75bc\u75db\u306e\u6539\u5584<br><br>\u305d\u306e\u4ed6\u306e\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u4e0d\u8db3\uff1a<br>NMDA\u578b\u53d7\u5bb9\u4f53\u306e\u8208\u596e\u306b\u3088\u308b\u30c0\u30e1\u30fc\u30b8<br>\u8133\u8840\u7ba1\u308c\u3093\u7e2e\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u306f<br>NMDA\u578b\u53d7\u5bb9\u4f53\u3068\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u306e\u7d50\u5408\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u8208\u596e\u3092\u6291\u3048\u308b<br>\u21d2\u8133\u795e\u7d4c\u7d30\u80de\u306e\u4fdd\u8b77<br><br>\u4e00\u65b9\u3001GABA\u3092\u6291\u5236<br>\u7b4b\u8089\u306e\u7dca\u5f35\u304c\u3086\u308b\u304f\u306a\u3063\u3066\u3001\u30e1\u30f3\u30bf\u30eb\u3082\u5b89\u5b9a\u3001\u5bdd\u4ed8\u304d\u3082\u3088\u304f\u306a\u308b<br>HPA\u8ef8\u306e\u8abf\u6574\u3082\u884c\u3046<br><br><span class=\"has-inline-color 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