{"id":7362,"date":"2020-12-30T08:28:00","date_gmt":"2020-12-29T23:28:00","guid":{"rendered":"http:\/\/www.itaya.or.jp\/?p=7362"},"modified":"2022-04-21T22:48:27","modified_gmt":"2022-04-21T13:48:27","slug":"covid-19%e3%81%ab%e9%96%a2%e9%80%a3%e3%81%99%e3%82%8b%e8%ab%96%e6%96%873","status":"publish","type":"post","link":"https:\/\/www.itaya.or.jp\/?p=7362","title":{"rendered":"COVID-19\u306b\u95a2\u9023\u3059\u308b\u8ad6\u65873"},"content":{"rendered":"\n

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\u201dCombining Antivirals and Immunomodulators to Fight COVID-19\u201d
\u3068\u3044\u3046\u8ad6\u6587\u306e\u7d9a\u304d\u3067\u3059\u3002

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\"\"
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INF\u03b1\/\u03b2\u304c\u3057\u3063\u304b\u308a\u3068\u50cd\u304d\uff08\u8d64\uff09\u3001\u708e\u75c7\u304c\u53ce\u675f\u3059\u308b\u3053\u3068\u3067\u3001
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INF\u03b1\/\u03b2\u304c\u3042\u307e\u308a\u3067\u306a\u304b\u3063\u305f\u5834\u5408\u3067\u3001\u30a6\u30a4\u30eb\u30b9\u3082\u3042\u307e\u308a\u6e1b\u3089\u305a\u3001
\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u304c\u5927\u91cf\u306b\u5206\u6ccc\u3055\u308c\u308b\u306e\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002
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\u3000\u8272\u3005\u306a\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u7523\u751f\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\uff09
\u2191
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\u3053\u306e\u56f3\u3001\u3069\u3053\u304b\u3067\u4f3c\u305f\u3088\u3046\u306a\u3082\u306e\u3092\u898b\u305f\u899a\u3048\u304c\u3042\u308a\u307e\u305b\u3093\u304b\uff1f

6\u6708\u306b\u81ea\u7136\u514d\u75ab\u306e\u8a71\u3092\u3057\u307e\u3057\u305f\u3002
\uff1e\u65b0\u578b\u30b3\u30ed\u30ca\u611f\u67d3\u75c7\u3068\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3<\/a>

\u3053\u3053\u3067\u7d39\u4ecb\u3057\u305f\u8ad6\u6587\uff1a
Type I and Type III Interferons ? Induction, Signaling, Evasion, and Application to Combat COVID-19<\/a>
\uff08I\u578b\u30fbIII\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\uff1a\u8a98\u5c0e\u3001\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3001\u56de\u907f\u3068COVID-19\u306e\u6cbb\u7642\u6226\u7565\uff09

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\"\"
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\u305d\u308c\u304cCOVID-19\u3092\u91cd\u75c7\u5316\u3055\u305b\u308b\u4e00\u3064\u306e\u8981\u56e0\u3068\u3082\u8003\u3048\u3089\u308c\u307e\u3059\u3002

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INF\u03b21a\u306f\u52b9\u304b\u306a\u304b\u3063\u305f\u3068\u3044\u3046\u5831\u544a\u3067\u3057\u305f\u3002
\u3053\u308c\u306f\u3069\u3046\u3057\u3066\u3067\u3057\u3087\u3046\u304b\uff1f

\u3053\u3053\u3067\u3001\u6700\u521d\u306e\u8ad6\u6587\u3001
\u201dRepurposed Antiviral Drugs for Covid-19 ? Interim WHO Solidarity Trial Results\u201d
\u306e\u3001\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u3092\u3082\u3046\u4e00\u5ea6\u3088\u304f\u8aad\u3093\u3067\u307f\u307e\u3057\u3087\u3046\u3002

INF\u03b21a\u306f\u3001\uff08\u6295\u4e0e\u7fa4\u3068\u975e\u6295\u4e0e\u7fa4\u306b\uff09\u632f\u308a\u5206\u3051\u3089\u308c\u305f\u65e5\u3068
\u305d\u308c\u304b\u30893\u65e5\u76ee\u30016\u65e5\u76ee\u306b\u76ae\u4e0b\u6ce8\u3067\u6295\u4e0e\u3055\u308c\u3066\u3044\u307e\u3059\u3002

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\u5c02\u9580\u5bb6\u3067\u306f\u306a\u3044\u306e\u3067\u3001\u9593\u9055\u3063\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001
\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u306b\u66b4\u9732\u3055\u308c\u305f\u3070\u304b\u308a\u306e\u3001
\u307e\u3060\u767a\u75c7\u3059\u308b\u524d\u306b\u6295\u4e0e\u3059\u308b\u306e\u304c
\u6700\u3082\u52b9\u679c\u7684\u306a\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f
\u3064\u307e\u308a\u3001\u6fc3\u539a\u63a5\u89e6\u8005\u306b\u4f7f\u3046\u65b9\u304c\u3044\u3044\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u3002

\u305f\u3060\u3001\u305d\u308c\u306b\u306f\u85ac\u5264\u306b\u91cd\u5927\u306a\u526f\u4f5c\u7528\u304c\u306a\u3044\u3053\u3068\u304c\u524d\u63d0\u306b\u306a\u308a\u307e\u3059\u3002
\u767a\u75c7\u3059\u308b\u304b\u3057\u306a\u3044\u304b\u5206\u304b\u3089\u306a\u3044\u6642\u70b9\u3067\u6295\u4e0e\u3059\u308b\u306e\u306f
\u502b\u7406\u7684\u306a\u554f\u984c\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002

\u3068\u3001\u3053\u3053\u307e\u3067\u66f8\u304d\u7d42\u3048\u305f\u3068\u3053\u308d\u3067\u3001
SARS-CoV-2\u3068\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u306e\u4e88\u9632\u52b9\u679c\u306b\u95a2\u3059\u308b\u8ad6\u6587\u304c\u306a\u3044\u304b\u306a\u3068
\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u3067\u63a2\u3057\u3066\u3044\u305f\u3068\u3053\u308d\u3001
SARS-CoV-2\u304c\u6301\u3064\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u3072\u3068\u3064ORF3b\u306b\u3001
\u5f37\u3044\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u6291\u5236\u6d3b\u6027\u52b9\u679c\u304c\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u306d\u3002
\uff1e\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u7523\u751f\u3092\u6291\u5236\u3059\u308bSARS-CoV-2\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u767a\u898b<\/a>
\uff1eSARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant<\/a>
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<\/p>\n\n\n\n


<\/p>\n","protected":false},"excerpt":{"rendered":"

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