{"id":7006,"date":"2020-06-22T08:28:00","date_gmt":"2020-06-21T23:28:00","guid":{"rendered":"http:\/\/www.itaya.or.jp\/?p=7006"},"modified":"2022-04-21T22:51:41","modified_gmt":"2022-04-21T13:51:41","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e6%84%9f%e6%9f%93%e7%97%87%e3%81%a8%e3%83%97%e3%83%ac%e3%83%9c%e3%83%86%e3%83%a9%e8%8f%8c3","status":"publish","type":"post","link":"https:\/\/www.itaya.or.jp\/?p=7006","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u611f\u67d3\u75c7\u3068\u30d7\u30ec\u30dc\u30c6\u30e9\u83cc3"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u305d\u308d\u305d\u308d\u6b21\u306e\u8a71\u984c\u306b\u884c\u3053\u3046\u3068\u601d\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u304c\u3001<br>\u30cd\u30c3\u30c8\u3092\u3055\u307e\u3088\u3063\u3066\u3044\u308b\u3068COVID-19\u306e\u8a18\u4e8b\u306b\u76ee\u304c\u884c\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002<br><br>Prevotella\u83cc\u304c\u91cd\u75c7\u5316\u306e\u771f\u72af\u4eba\u3068\u3044\u3046\u8aac\u306f\u3001<br><a aria-label=\"\u5426\u5b9a\u3055\u308c\u3066\u3044\u308b (\u65b0\u3057\u3044\u30bf\u30d6\u3067\u958b\u304f)\" rel=\"noreferrer noopener\" href=\"http:\/\/www.itaya.or.jp\/?p=6994\" target=\"_blank\">\u5426\u5b9a\u3055\u308c\u3066\u3044\u308b<\/a>\u3068\u524d\u3005\u56de\u306b\u66f8\u304d\u307e\u3057\u305f\u3002<br><br>\u305f\u3060\u3001\u3053\u3093\u306a\u8a18\u4e8b\u304c\u51fa\u3066\u304d\u307e\u3057\u305f\u3002<br>5\u67086\u65e5\u4ed8\u3051\u306eBioinformatics\u3068\u3044\u3046\u96d1\u8a8c\u306e\u30b5\u30a4\u30c8\u3067\u3059\u3002<br>\uff1e<a aria-label=\"COVID-2019-associated overexpressed Prevotella proteins mediated  host?pathogen interactions and their role in coronavirus  outbreak\n (\u65b0\u3057\u3044\u30bf\u30d6\u3067\u958b\u304f)\" rel=\"noreferrer noopener\" href=\"https:\/\/academic.oup.com\/bioinformatics\/advance-article\/doi\/10.1093\/bioinformatics\/btaa285\/5831291?searchresult=1\" target=\"_blank\">COVID-2019-associated overexpressed Prevotella proteins mediated  host?pathogen interactions and their role in coronavirus  outbreak<br><\/a><br>Abstract\u3092Google\u7ffb\u8a33\u3057\u307e\u3057\u305f\u3002<br>********<br>\u52d5\u6a5f<br>\u4e2d\u56fd\u306e\u6b66\u6f22\u3067\u59cb\u307e\u3063\u305fCOVID-2019\u306e\u767a\u751f\u306f\u3001\u6025\u901f\u306a\u611f\u67d3\u3068\u6df1\u523b\u306a\u6b7b\u8005\u306b\u3088\u308a\u4e16\u754c\u7684\u306a\u8105\u5a01\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002  \u6700\u8fd1\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\uff08COVID-2019\u306e\u539f\u56e0\u3067\u3042\u308b\uff09SARS-CoV-2\u306e\u5168\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b9\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002  \u3055\u3089\u306b\u3001\u611f\u67d3\u3057\u305f\u60a3\u8005\u306e\u80ba\u30e1\u30bf\u30b2\u30ce\u30e0\u7814\u7a76\u306b\u3088\u308a\u3001\u7279\u5b9a\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u8c4a\u5bcc\u306b\u751f\u6210\u3059\u308b\u3001\u30d7\u30ec\u30dc\u30c6\u30e9\u5c5e\u83cc\u306e\u904e\u5270\u767a\u73fe\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002  SARS-CoV-2\u3068\u30d2\u30c8\u30d7\u30ed\u30c6\u30aa\u30fc\u30e0\u306b\u3088\u308b\u904e\u5270\u767a\u73fe\u30d7\u30ec\u30dc\u30c6\u30e9\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u306e\u9593\u306e\u30db\u30b9\u30c8?\u75c5\u539f\u4f53\u30bf\u30f3\u30d1\u30af\u8cea?\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u5206\u6790\u3092\u884c\u3044\u307e\u3057\u305f\u3002  COVID-2019\u306e\u91cd\u75c7\u5ea6\u306b\u304a\u3051\u308b\u5f79\u5272\u3092\u7406\u89e3\u3059\u308b\u305f\u3081\u306b\u3001\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u904e\u5270\u5206\u6790\u3082\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002<br><br>\u7d50\u679c<br>\u904e\u5270\u767a\u73fe\u3057\u305f\u30d7\u30ec\u30dc\u30c6\u30e9\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u3092\u4fc3\u9032\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002  \u7d50\u679c\u306b\u3088\u308b\u3068\u3001\u30a6\u30a4\u30eb\u30b9\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u306f\u306a\u304f\u30d7\u30ec\u30dc\u30c6\u30e9\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3001COVID-2019\u306e\u81e8\u5e8a\u7684\u91cd\u75c7\u5ea6\u306e\u5897\u52a0\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308bNF-kB\u3068\u306e\u8907\u6570\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002  Prevotella\u306fCOVID-2019\u306e\u767a\u751f\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u75be\u60a3\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u7406\u89e3\u3057\u3001\u6cbb\u7642\u7d50\u679c\u3092\u6539\u5584\u3059\u308b\u305f\u3081\u306b\u91cd\u8981\u3067\u3059\u3002<br>********<br><br>NF-kB\uff08\u30a8\u30cc\u30a8\u30d5\u30fb\u30ab\u30c3\u30d1\u30fc\u30fb\u30d3\u30fc\u3068\u8aad\u3080\u3089\u3057\u3044\uff09\u306f\u3001<br>\u7d30\u80de\u5185\u3067DNA\u21d2\uff4dRNA\u21d2\u30bf\u30f3\u30d1\u30af\u8cea\u751f\u6210\u304c\u884c\u308f\u308c\u308b\u904e\u7a0b\u306e<br>DNA\u21d2\uff4dRNA\u306e\u3068\u3053\u308d\u3067\u50cd\u304f\u30bf\u30f3\u30d1\u30af\u8cea\u307f\u305f\u3044\u3067\u3059\u306d\u3002<br><br>\u3053\u306e\u3042\u305f\u308a\u306e\u3053\u3068\u3063\u3066\u3001\u4eca\u306f\u9ad8\u6821\u751f\u3067\u3082\u7fd2\u3046\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<br>\u50d5\u306f40\u5e74\u8fd1\u304f\u524d\u306e\u77e5\u8b58\u3092\u3082\u3068\u306b\u30cd\u30c3\u30c8\u3067\u7528\u8a9e\u3092\u8abf\u3079\u3066<br>\u77e5\u8b58\u306e\u9699\u9593\u3092\u57cb\u3081\u3066\u3044\u308b\u72b6\u614b\u3067\u3059\u3002<br><br>\u8ad6\u6587\u306e\u4e2d\u8eab\u3001\u7279\u306b\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306b\u3064\u3044\u3066\u306f<br>\u304b\u306a\u308a\u3061\u3093\u3077\u3093\u304b\u3093\u3077\u3093\u306a\u3093\u3067\u3059\u304c\u3001<br>20\u500b\u306eSARS-CoV-2\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3001<br>8\u3064\u306e\u30d2\u30c8\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u307f\u3068\u76f8\u4e92\u4f5c\u7528\u3057\u3066\u3044\u308b\u3068\u4e88\u6e2c\u3055\u308c\u307e\u3057\u305f\u3002<br><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"191\" class=\"wp-image-7007\" style=\"width: 300px;\" alt=\"\" src=\"http:\/\/www.itaya.or.jp\/wp-content\/uploads\/2020\/06\/image-1.png\" srcset=\"https:\/\/www.itaya.or.jp\/wp-content\/uploads\/2020\/06\/image-1.png 522w, https:\/\/www.itaya.or.jp\/wp-content\/uploads\/2020\/06\/image-1-400x254.png 400w, https:\/\/www.itaya.or.jp\/wp-content\/uploads\/2020\/06\/image-1-135x86.png 135w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><br>(Fig.1 <em>Bioinformatics<\/em>, btaa285)<br><br>\u3053\u308c\u306b\u5bfe\u3057\u3066\u3001Prevotella\u83cc\u306e\u65b9\u306f18\u500b\u306e\u904e\u5270\u767a\u73fe\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3001<br>3431\u500b\u306e\u30d2\u30c8\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u76f8\u4e92\u4f5c\u7528\u3057\u3066\u3044\u308b\u3089\u3057\u3044\u306e\u3067\u3059\u3002<br><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" class=\"wp-image-7013\" style=\"width: 300px;\" alt=\"\" src=\"http:\/\/www.itaya.or.jp\/wp-content\/uploads\/2020\/06\/image-2.png\" srcset=\"https:\/\/www.itaya.or.jp\/wp-content\/uploads\/2020\/06\/image-2.png 522w, https:\/\/www.itaya.or.jp\/wp-content\/uploads\/2020\/06\/image-2-400x320.png 400w, https:\/\/www.itaya.or.jp\/wp-content\/uploads\/2020\/06\/image-2-115x92.png 115w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><br>(Fig.2 <em>Bioinformatics<\/em>, btaa285)<br><br>\u3060\u304b\u3089\u3084\u3063\u3071\u308a\u4f55\u304b\u60aa\u3055\u3092\u3057\u3066\u3044\u308b\u3093\u3058\u3083\u306a\u3044\u304b\u3001<br>\u3068\u3044\u3046\u3053\u3068\u306a\u306e\u3067\u3057\u3087\u3046\u3002<br>\u3082\u3046\u5c11\u3057\u52c9\u5f37\u3057\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u305d\u308d\u305d\u308d\u6b21\u306e\u8a71\u984c\u306b\u884c\u3053\u3046\u3068\u601d\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u304c\u3001\u30cd\u30c3\u30c8\u3092\u3055\u307e\u3088\u3063\u3066\u3044\u308b\u3068COVID-19\u306e\u8a18\u4e8b\u306b\u76ee\u304c\u884c\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002 Prevotella\u83cc\u304c\u91cd\u75c7\u5316\u306e\u771f\u72af\u4eba\u3068\u3044\u3046\u8aac\u306f\u3001\u5426\u5b9a\u3055\u308c\u3066\u3044\u308b\u3068\u524d\u3005\u56de\u306b\u66f8\u304d\u307e\u3057\u305f\u3002 \u305f\u3060\u3001\u3053\u3093\u306a\u8a18 &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[89,6],"tags":[67],"class_list":["post-7006","post","type-post","status-publish","format-standard","hentry","category-covid-19","category-blog","tag-covid-19"],"_links":{"self":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/7006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7006"}],"version-history":[{"count":6,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/7006\/revisions"}],"predecessor-version":[{"id":7016,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/7006\/revisions\/7016"}],"wp:attachment":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7006"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7006"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}