{"id":6936,"date":"2020-06-11T08:28:00","date_gmt":"2020-06-10T23:28:00","guid":{"rendered":"http:\/\/www.itaya.or.jp\/?p=6936"},"modified":"2020-06-17T02:14:19","modified_gmt":"2020-06-16T17:14:19","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e6%84%9f%e6%9f%93%e7%97%87%e3%81%a8%e3%83%97%e3%83%ac%e3%83%9c%e3%83%86%e3%83%a9%e8%8f%8c2","status":"publish","type":"post","link":"https:\/\/www.itaya.or.jp\/?p=6936","title":{"rendered":"\u6162\u6027\u75be\u60a3\u3068\u30d7\u30ec\u30dc\u30c6\u30e9\u83cc"},"content":{"rendered":"\n

\u6628\u65e5\u306b\u7d9a\u304d\u3001\u79d1\u5b66\u306e\u5148\u751f\u304c\u66f8\u304b\u308c\u305f\u6295\u7a3f\uff1a
Covid-19 : Et si on ne cherchait pas a tuer le virus\u2026
\u306b\u3064\u3044\u3066\u66f8\u3053\u3046\u3068\u601d\u3063\u305f\u306e\u3067\u3059\u304c\u3001
\u305d\u306e\u524d\u306b\u3001Prevotella\u83cc\u3068\u5168\u8eab\u306e\u708e\u75c7\u306b\u3064\u3044\u3066\u3001
\u6559\u79d1\u66f8\u7684\u306a\u8a73\u3057\u3044\u8ad6\u6587\u304c\u3042\u308a\u307e\u3057\u305f\u306e\u3067\u7d39\u4ecb\u3057\u307e\u3059\u3002

\u201dThe immune response to Prevotella bacteria in chronic in?ammatory disease<\/a>\uff08\u6162\u6027\u708e\u75c7\u6027\u75be\u60a3\u306b\u304a\u3051\u308b\u30d7\u30ec\u30dc\u30c6\u30e9\u83cc\u306b\u5bfe\u3059\u308b\u514d\u75ab\u53cd\u5fdc\uff09\u201d
\u51fa\u5178\u306fImmunology\u3067\u3059\u3002

\u5fae\u751f\u7269\u53e2\u306f\u3001\u514d\u75ab\u306e\u767a\u9054\u3001\u514d\u75ab\u53cd\u5fdc\u304a\u3088\u3073\u4ee3\u8b1d\u3092\u5f62\u4f5c\u308a\u3001
\u75c5\u539f\u4f53\u306e\u4fb5\u5165\u304b\u3089\u4fdd\u8b77\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001
\u4eba\u9593\u306e\u5065\u5eb7\u3068\u75be\u60a3\u306b\u304a\u3044\u3066\u4e2d\u5fc3\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002

\u6700\u8fd1\u306e\u4eba\u9593\u306b\u304a\u3051\u308b\u7814\u7a76\u3067\u3001
\u7c98\u819c\u90e8\u4f4d\u3067\u306ePrevotella\u83cc\u306e\u5897\u52a0\u304c\u3001\u6b6f\u5468\u708e\u3001\u7d30\u83cc\u6027\u81a3\u708e\u3001
\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3001\u4ee3\u8b1d\u969c\u5bb3\u304a\u3088\u3073\u4f4e\u5ea6\u306e\u5168\u8eab\u6027\u708e\u75c7\u3092\u542b\u3080
\u9650\u5c40\u6027\u304a\u3088\u3073\u5168\u8eab\u6027\u75be\u60a3\u3068\u95a2\u9023\u4ed8\u3051\u3089\u308c\u308b\u69d8\u306b\u306a\u308a\u307e\u3057\u305f\u3002

Prevotella\u83cc\u306f\u3001\u30d0\u30af\u30c6\u30ed\u30a4\u30c7\u30b9\u9580\u306e\u5acc\u6c17\u6027\u30b0\u30e9\u30e0\u9670\u6027\u7d30\u83cc\u3067\u3001
\u4e3b\u306b\uff08\u8178\u306e\u4e0a\u76ae\u3092\u8cab\u3044\u3066\u3044\u308b\u6a39\u72b6\u7d30\u80de\u304c\u3082\u3064\uff09Toll\u69d8\u53d7\u5bb9\u4f532\u3092
\u6d3b\u6027\u5316\u3057\u3001\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f323\uff08IL-23\uff09\u3084IL-1\u306a\u3069\u306e
\u6297\u539f\u63d0\u793a\u7d30\u80de\u306b\u3088\u308bTh17\u6975\u6027\u5316\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u7523\u751f\u306b
\u3064\u306a\u304c\u308a\u307e\u3059\u3002\u3055\u3089\u306b\u3001Prevotella\u306f\u4e0a\u76ae\u7d30\u80de\u3092\u523a\u6fc0\u3057\u3066IL-8\u3001IL-6
\u304a\u3088\u3073CCL20\u3092\u751f\u6210\u3057\u307e\u3059\u3002

\u7d50\u69cb\u96e3\u3057\u3044\u8a71\u304c\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u304c\u3001\u8981\u306f\u3001
Prevotella\u83cc\u304c\u8178\u7c98\u819c\u306b\u4ed8\u7740\u3059\u308b\u3068\u3001
\u305d\u3053\u3067\u8178\u7c98\u819c\u306e\u8868\u9762\u3092\u76e3\u8996\u3057\u3066\u3044\u308b\u6a39\u72b6\u7d30\u80de\u304c\u53cd\u5fdc\u3057\u3001
\u514d\u75ab\u306b\u95a2\u9023\u3059\u308b\u30b7\u30b0\u30ca\u30eb\u304c\u7523\u751f\u3055\u308c\u3001
\u3053\u306e\u30b7\u30b0\u30ca\u30eb\u304c\u5168\u8eab\u306b\u4f1d\u3048\u3089\u308c\u3001
\u5168\u8eab\u6027\u708e\u75c7\u6027\u75be\u60a3\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002

\u3053\u3046\u3057\u305f\u5c40\u6240\u306e\u708e\u75c7\u304c\u5168\u8eab\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u3092
\u75c5\u5de3\u611f\u67d3\u3068\u547c\u3073\u307e\u3059\u304c\u3001\u6b6f\u5468\u75c5\u3068\u95a2\u9023\u306e\u3042\u308b
Prevotella intermedia\u3084P. gingivalis\u306a\u3069\u3068\u3044\u3063\u305f\u83cc\u3084\u3001
\u8178\u5185\u306e\u5b58\u5728\u3059\u308bPrevotella copri\u3068\u3044\u3063\u305fPrevotella\u83cc\u304c
\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306e\u767a\u75c7\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002

\u540c\u8ad6\u6587\u306b\u3042\u3063\u305f\u56f3\u3067\u3059\u3002
\"\"

\u540c\u3058\u69d8\u306bPrevotella\u83cc\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u601d\u308f\u308c\u308b\u3082\u306e\u306b
\u7d30\u83cc\u6027\u81a3\u708e\u3082\u3042\u308b\u305d\u3046\u3067\u3059\u3002

\u666e\u6bb5\u306f\u81a3\u306e\u4e2d\u306f\u81a3\u5171\u751f\u4e73\u9178\u687f\u83cc\uff08Lactobacillus crispatus\u3001
Lactobacillus iners\u304a\u3088\u3073\/\u307e\u305f\u306fLactobacillus acidophilus\uff09
\u3068\u3044\u3046\u83cc\u304c\u3044\u308b\u305d\u3046\u306a\u306e\u3067\u3059\u304c\u3001\u3053\u3046\u3057\u305f\u5171\u751f\u83cc\u304c\u6e1b\u5c11\u3059\u308b\u3068
Prevotella\u83cc\u304c\u5897\u3048\u3066\u7d30\u83cc\u6027\u81a3\u708e\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001
\u305d\u306e\u5f71\u97ff\u306f\u5168\u8eab\u306b\u3082\u4f1d\u642c\u3055\u308c\u308b\u305d\u3046\u3067\u3059\u3002

\u8178\u5185\u7d30\u83cc\u3068\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u3082\u95a2\u9023\u304c\u3042\u308b\u3088\u3046\u3067\u3059\u3002
Prevotella copri\u3068Bacteroides vulgatus\u306e\u4e21\u65b9\u306e\u5897\u52a0\u306f
\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\uff08II\u578b\u7cd6\u5c3f\u75c5\uff09\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u304c\u3001
\u3053\u306e\uff12\u7a2e\u306f\u8178\u3067\u76f8\u4e92\u306b\u6392\u4ed6\u7684\u306a\u3093\u3060\u305d\u3046\u3067\u3001
\u9ad8\u7e4a\u7dad\u98df\u306e\u5f8c\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u4ee3\u8b1d\u304c\u6539\u5584\u3055\u308c\u305f\u5834\u5408\u306f\u3001
\u8178\u5185\u7d30\u83cc\u53e2\u306fPrevotella\u83cc\u306b\u5bcc\u3093\u3060\u3082\u306e\u306b\u306a\u308b\u3089\u3057\u304f\u3001
\u5358\u306b\u7d30\u83cc\u554f\u984c\u3060\u3051\u3067\u3082\u306a\u304f\u98df\u4e8b\u306b\u3082\u95a2\u9023\u3057\u3066\u3044\u308b\u69d8\u3067\u3059\u3002

\u3053\u308c\u306b\u5bfe\u3057\u3066\u3001\u9762\u767d\u3044\u306e\u304c\u3001
\u5598\u606f\u3084COPD\uff08\u6162\u6027\u9589\u585e\u6027\u80ba\u75be\u60a3\uff09\u3067\u306f\u3001Prevotella\u83cc\u5c5e\u306f
\u6e1b\u5c11\u3059\u308b\u306e\u3060\u305d\u3046\u3067\u3059\u3002
\u2191\u3053\u3053\u3001\u307e\u3060\u81ea\u5206\u306e\u4e2d\u3067\u6d88\u5316\u3057\u304d\u308c\u3066\u3044\u306a\u3044\u306e\u3067\u3059\u304c\u3001
\u5598\u606f\u3084COPD\u3067\u306fPrevotella\u83cc\u304c\u5c11\u306a\u304f\u306a\u3063\u305f\u304b\u308f\u308a\u306b
\u5225\u306e\u83cc\u304c\u5897\u3048\u3066\u3044\u308b\u305d\u3046\u3067\u3001
Prevotella\u83cc\u304c\u5c11\u91cf\u3044\u308b\u3053\u3068\u3067\u3001\u5f31\u3044\u523a\u6fc0\u3092\u8eab\u4f53\u306b\u4e0e\u3048\u308b\u3053\u3068\u3067
\u5f37\u3044\u83cc\u306e\u4fb5\u5165\u3092\u9632\u3044\u3067\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u306a\u306e\u304b\u3068\u601d\u3044\u307e\u3059\u3002
\uff08\u9593\u9055\u3063\u3066\u3044\u305f\u3089\u3001\u3053\u3063\u305d\u308a\u3068\u6559\u3048\u3066\u4e0b\u3055\u3044\uff09
<\/p>\n","protected":false},"excerpt":{"rendered":"

\u6628\u65e5\u306b\u7d9a\u304d\u3001\u79d1\u5b66\u306e\u5148\u751f\u304c\u66f8\u304b\u308c\u305f\u6295\u7a3f\uff1aCovid-19 : Et si on ne cherchait pas a tuer le virus\u2026\u306b\u3064\u3044\u3066\u66f8\u3053\u3046\u3068\u601d\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u305d\u306e\u524d\u306b\u3001Prevotella\u83cc\u3068\u5168\u8eab\u306e\u708e\u75c7 …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[66],"class_list":["post-6936","post","type-post","status-publish","format-standard","hentry","category-blog","tag-66"],"_links":{"self":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/6936","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6936"}],"version-history":[{"count":6,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/6936\/revisions"}],"predecessor-version":[{"id":6983,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=\/wp\/v2\/posts\/6936\/revisions\/6983"}],"wp:attachment":[{"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6936"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6936"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.itaya.or.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6936"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}